Evidence map›Paper›PMID 39289340›Full record

ArticleNature communications2024

Atomic vacancies of molybdenum disulfide nanoparticles stimulate mitochondrial biogenesis.

Kanwar Abhay Singh, John Soukar, Mohammad Zulkifli, Anna Kersey, Giriraj Lokhande, Sagnika Ghosh, Aparna Murali, Natalie M Garza, Harman Kaur, Justin N Keeney and 6 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. 2D MoSNano convergence · 2026
    Article
  3. Review
  4. Intronic polyadenylation-derived long noncoding RNA modulates nucleolar integrity and function.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Designing the Next Generation of Biomaterials through Nanoengineering.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kanwar Abhay SinghDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.ORCID 0000-0001-9704-0495
John SoukarDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.ORCID 0000-0002-1175-2895
Mohammad ZulkifliDepartment of Biochemistry and Biophysics, College of Agriculture & Life Sciences, Texas A&M University, College Station, TX, USA.ORCID 0000-0002-9110-9508
Anna KerseyDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.
Giriraj LokhandeDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.
Sagnika GhoshDepartment of Biochemistry and Biophysics, College of Agriculture & Life Sciences, Texas A&M University, College Station, TX, USA.ORCID 0000-0003-2883-7008
Aparna MuraliDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.
Natalie M GarzaDepartment of Biochemistry and Biophysics, College of Agriculture & Life Sciences, Texas A&M University, College Station, TX, USA.
Harman KaurDepartment of Biochemistry and Biophysics, College of Agriculture & Life Sciences, Texas A&M University, College Station, TX, USA.
Justin N KeeneyDepartment of Cell biology and Genetics, College of Medicine, Texas A&M University, Bryan, TX, USA.ORCID 0000-0003-1748-0971
Ramu BanavathDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.ORCID 0000-0003-2618-4365
Hatice Ceylan KoydemirDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA.ORCID 0000-0002-8612-5167
Raquel SitcheranInterdisiplinary program in Genetics and Genomics, Texas A&M University, College Station, TX, USA.ORCID 0000-0001-8916-9707
Irtisha SinghDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA. isingh@tamu.edu.ORCID 0000-0002-9460-3587
Vishal M GohilInterdisiplinary program in Genetics and Genomics, Texas A&M University, College Station, TX, USA. vgohil@tamu.edu.ORCID 0000-0002-9920-2563
Akhilesh K GaharwarDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA. gaharwar@tamu.edu.ORCID 0000-0002-0284-0201

Funding

Mineralomics: Designing mineral based therapeutics to control and direct cell functionDP2EB026265 · NIBIB · TEXAS ENGINEERING EXPERIMENT STATION · PI GAHARWAR, AKHILESH K. · 2017 to 2021
$2.4M
Mitochondrial Copper BiologyR35GM152102 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI Vishal Mahendrasingh Gohil · 2024 to 2026
$1.7M
Osteoinductive Nanosilicate-Based Biomaterials for In Situ Craniomaxillofacial Bone RegenerationR01DE032031 · NIDCR · TEXAS ENGINEERING EXPERIMENT STATION · PI CARL A. GREGORY, Akhilesh K. Gaharwar · 2024 to 2026
$1.7M
Impact of Emotions on Treatment Decisions About Low-Risk Thyroid CancerK08CA230204 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI PITT, SUSAN C · 2018 to 2023
$1.4M
Investigating the role Ikaros variants in multiple myeloma pathophysiology and drug sensitivityR01CA282251 · NCI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI Irtisha Singh · 2024 to 2026
$1.1M
Mechanisms of elesclomol-mediated copper delivery to cuproenzymes in cellsR01GM143630 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI GOHIL, VISHAL MAHENDRASINGH · 2021 to 2023
$979k
Investigating Pathophysiology of Glioma Stem Cells in 3D Bioprinted Vascularized Glioblastoma ModelR21NS121945 · NINDS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI SINGH, IRTISHA · 2022 to 2023
$403k
Cancer Prevention and Research Institute of Texas (Cancer Prevention Research Institute of Texas) RP230204NCI NIH HHS R01 CA282251NIBIB NIH HHS DP2 EB026265NIDCR NIH HHS R01 DE032031NIGMS NIH HHS R01 GM143630NIGMS NIH HHS R35 GM152102NINDS NIH HHS R21 NS121945United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs (CDMRP) W81XWH2210932U.S. Department of Health & Human Services | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) EB026265U.S. Department of Health & Human Services | NIH | National Institute of Dental and Craniofacial Research (NIDCR) DE032031U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R01GM143630U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35GM152102U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS121945U.S. Department of Health & Human Services | NIH | NCI | Division of Cancer Epidemiology and Genetics, National Cancer Institute (National Cancer Institute Division of Cancer Epidemiology and Genetics) CA282251
6 · The paper itself

Abstract

Diminished mitochondrial function underlies many rare inborn errors of energy metabolism and contributes to more common age-associated metabolic and neurodegenerative disorders. Thus, boosting mitochondrial biogenesis has been proposed as a potential therapeutic approach for these diseases; however, currently we have a limited arsenal of compounds that can stimulate mitochondrial function. In this study, we designed molybdenum disulfide (MoS

Indexed as

DisulfidesMitochondriaMolybdenumNanoparticlesAdenosine TriphosphateAnimalsDNA, MitochondrialHumansMiceMitochondrial ProteinsOrganelle BiogenesisAdenosine TriphosphateDisulfidesDNA, MitochondrialMitochondrial ProteinsMolybdenummolybdenum disulfide

Identifiers

PMID39289340
PMCPMC11408498

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.