Evidence map›Paper›PMID 39289520›Full record

ArticleEye (London, England)2024

The central retina vessel density and foveal avascular zone values of 792 healthy adults using optical coherence tomography angiography.

Hamid Reza Heidarzadeh, Mojtaba Abrishami, Elaheh Ebrahimi Miandehi, Nasser Shoeibi, Mohammad Reza Ansari Astaneh, Seyedeh Maryam Hosseini, Majid Abrishami, Saeed Eslami, Ali Bolouki

Abstract read
In one paragraph

Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hamid Reza HeidarzadehEye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID 0000-0003-2811-9073
Mojtaba AbrishamiEye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID 0000-0003-2001-7929
Elaheh Ebrahimi MiandehiPersian Cohort Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Nasser ShoeibiEye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID 0000-0003-3544-0105
Mohammad Reza Ansari AstanehEye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyedeh Maryam HosseiniEye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Majid AbrishamiEye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Saeed EslamiPharmaceutical Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Ali BoloukiEye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. boloukia991@mums.ac.ir.ORCID 0009-0004-6931-4523

Funding

Mashhad University of Medical Sciences (MUMS) 990069
6 · The paper itself

Abstract

BACKGROUND/

objectivesTo determine normal macular vessel density (VD) and foveal avascular zone (FAZ) values using optical coherence tomography angiography (OCTA) analysis in healthy adults. SUBJECTS/

methodsAs part of the Prospective Epidemiological Research Studies in Iran (PERSIAN) Organizational Cohort study at Mashhad University of Medical Sciences (POCM), we conducted a cross-sectional study using 3 × 3 and 6 × 6 mm OCTA scans to evaluate the VD of the macular superficial capillary plexus (SCP), deep capillary plexus (DCP), and the FAZ area in healthy adults.

resultsThe study included 792 participants, with a mean age of 39.8 ± 6.8 years. There were 359 males with a mean age of 39.9 ± 7.8 years and 440 females with a mean age of 39.4 ± 6 years. The mean values of various parameters were measured, including the right eye whole image SCP and DCP VDs, FAZ area, FAZ perimeter, and fovea VD in a 300 µm wide zone around FAZ (FD). These values were found to be 45.9 ± 2.6%, 50.2 ± 3%, 0.3 ± 0.1mm

conclusionOur study established standard SCP and DCP VD values influenced by age and gender. Age correlates negatively with both, DCP VDs correlate negatively with height and weight, and SCP VDs correlate positively with diastolic blood pressure.

Indexed as

AngiographyFovea CentralisMicrovascular DensityRetinal VesselsTomography, Optical CoherenceAdultAge FactorsCross-Sectional StudiesFemaleHealthy VolunteersHumansIranLinear ModelsMaleMiddle AgedProspective Studies

Identifiers

PMID39289520
PMCPMC11621524

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.