Evidence mapPaperPMID 39290278Full record

ArticleHeliyon2024

Visual analysis on ferroptosis and its cross-talk to coronavirus disease 2019 (COVID-19).

Junda Zhou, Wenjia Ni, Xianqin Zhang, Meng Yang, Xin Liu, Jinlin Guo, Jian Li, Qi Zhao, Hang Deng, Hanyue Lei and 3 more

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Junda ZhouCollege of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
Wenjia NiKey Laboratory of Non-Coding RNA and Drug Discovery at Chengdu Medical College of Sichuan Province, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Xianqin ZhangKey Laboratory of Non-Coding RNA and Drug Discovery at Chengdu Medical College of Sichuan Province, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Meng YangKey Laboratory of Non-Coding RNA and Drug Discovery at Chengdu Medical College of Sichuan Province, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Xin LiuCollege of Public Health, Chengdu Medical College, China.
Jinlin GuoChengdu University of Traditional Chinese Medicine, China.
Jian LiSchool of Basic Medical Sciences, Chengdu University, Chengdu, 610106, China.
Qi ZhaoCollege of Food and Biological Engineering, Chengdu University, Chengdu, 610106, China.
Hang DengKey Laboratory of Non-Coding RNA and Drug Discovery at Chengdu Medical College of Sichuan Province, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Hanyue LeiKey Laboratory of Non-Coding RNA and Drug Discovery at Chengdu Medical College of Sichuan Province, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610500, Sichuan, China.
Lin ZhangDepartment of Clinical Pharmacy, ShaoXing People's Hospital, ShaoXing Hospital of ZheJiang University, China.
Hai LiaoCollege of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
Xu JiaKey Laboratory of Non-Coding RNA and Drug Discovery at Chengdu Medical College of Sichuan Province, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610500, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ferroptosis is a new type of programmed cell death. Although ferroptosis has been studied in various aspects, there has been no visual analysis of ferroptosis in coronavirus disease 2019 (COVID-19) to date. It is still a global health concern of the COVID-19 pandemic worldwide, three years after its outbreak. Yet the emergence of the mutant strain Omicron has caused a fourth wave of infections in many countries. The pathogenesis of COVID-19 is still undergoing extensive exploration, which holds paramount importance in mitigating future epidemics. Methods: For this study, CiteSpace 6.2 R4 software was used for bibliometric and visual atlas analysis of ferroptosis-related research, and the Genecards database was used to mine ferroptosis and COVID-19-related genes. Results: We found increasing studies about ferroptosis. China and the United States have demonstrated robust scientific innovation over recent years, with extensive collaboration between their institutions and authors. Ferroptosis and COVID-19 were seen to have 13 shared genes, which may be new targets for the treatment of COVID-19 in the future. Most of the shared genes are enriched in tumor necrosis factor (TNF) pathways. The majority of those genes are up-regulated under the cellular response to oxidative stress. Genes including Tumour necrosis factor (TNF), RELA proto-oncogene (RELA), Activating transcription factor 4 (ATF4), Cytochrome

Indexed as

BibliometricCitespaceCOVID-19FerroptosisVisual atlas

Identifiers

PMID39290278
PMCPMC11407094

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.