Evidence map›Paper›PMID 39291956›Full record

ArticleeLife2024

Ca

Audrey T Medeiros, Scott J Gratz, Ambar Delgado, Jason T Ritt, Kate M O'Connor-Giles

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Active Zone Maturation Controls Presynaptic Output and Release Mode and Is Regulated by Neuronal Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Article
  6. Article
  7. Neurodegenerative and Neurodevelopmental Roles for Bulk Lipid Transporters VPS13A and BLTP2.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Muscle-fiber specific genetic manipulation ofFrontiers in physiology · 2024
    Article
4 · The record

Corrections and comments

  • Update of
    Ca2024
5 · Who and what money

Authors and funding

5 authors.

Audrey T MedeirosNeuroscience Graduate Training Program, Brown University, Providence, United States.ORCID https://orcid.org/0000-0002-5562-4772
Scott J GratzDepartment of Neuroscience, Brown University, Providence, United States.ORCID https://orcid.org/0000-0002-0106-8336
Ambar DelgadoDepartment of Neuroscience, Brown University, Providence, United States.
Jason T RittDepartment of Neuroscience, Brown University, Providence, United States.ORCID https://orcid.org/0000-0003-3113-7977
Kate M O'Connor-GilesNeuroscience Graduate Training Program, Brown University, Providence, United States.ORCID https://orcid.org/0000-0002-2259-8408

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Cale Whitworth · 2014 to 2026
$13.5M
Interdisciplinary Predoctoral Neuroscience Training Program in the Neuroscience Graduate Program.T32MH020068 · NIMH · BROWN UNIVERSITY · PI LIPSCOMBE, DIANE, SHEINBERG, DAVID L · 1999 to 2025
$7.6M
Molecular mechanisms of synapse assembly and functionR01NS078179 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI O'CONNOR-GILES, KATHALEEN M · 2013 to 2023
$3.6M
Dynamic regulation of synaptic Ca2+ channel organizationF31NS122424 · NINDS · BROWN UNIVERSITY · PI MEDEIROS, AUDREY TAYLOR · 2021 to 2023
$140k
NIH HHS P40 OD018537NIMH NIH HHS T32 MH020068NINDS NIH HHS F31 NS122424NINDS NIH HHS F31NS122424NINDS NIH HHS R01 NS078179NINDS NIH HHS R01NS078179
6 · The paper itself

Abstract

Synaptic heterogeneity is a hallmark of nervous systems that enables complex and adaptable communication in neural circuits. To understand circuit function, it is thus critical to determine the factors that contribute to the functional diversity of synapses. We investigated the contributions of voltage-gated calcium channel (VGCC) abundance, spatial organization, and subunit composition to synapse diversity among and between synapses formed by two closely related

Indexed as

Calcium ChannelsDrosophila ProteinsSynapsesAnimalsDrosophilaDrosophila melanogasterMotor NeuronsSynaptic TransmissionCalcium ChannelsDrosophila Proteinsactive zonecalcium channelD. melanogasterneurosciencepresynaptic homeostasissynaptic diversityVGCC

Identifiers

PMID39291956
PMCPMC11410372

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.