Evidence map›Paper›PMID 39294173›Full record

ArticleNPJ vaccines2024

Low-frequency CD8

Daisuke Muraoka, Meng Ling Moi, Osamu Muto, Takaaki Nakatsukasa, Situo Deng, Chieko Takashima, Rui Yamaguchi, Shin-Ichi Sawada, Haruka Hayakawa, Thi Thanh Ngan Nguyen and 6 more

Abstract read
In one paragraph

Article in NPJ vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Daisuke Muraoka *Department of Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. d.muraoka@aichi-cc.jp.ORCID http://orcid.org/0000-0002-4493-7052
Meng Ling Moi *School of International Health, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan. sherry@m.u-tokyo.ac.jp.
Osamu MutoDivision of Cancer Systems Biology, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID http://orcid.org/0000-0003-3831-7612
Takaaki NakatsukasaDepartment of Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Situo DengDepartment of Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Chieko TakashimaDivision of Translational Oncoimmunology, Aichi Cancer Center Research Institute, Nagoya, Japan.
Rui YamaguchiDivision of Cancer Systems Biology, Aichi Cancer Center Research Institute, Nagoya, Japan.ORCID http://orcid.org/0000-0003-1224-227X
Shin-Ichi SawadaSynergy Institute for Futuristic Mucosal Vaccine Research and Development (cSIMVa), Chiba University, Chiba, Japan.
Haruka HayakawaSchool of International Health, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.
Thi Thanh Ngan NguyenInstitute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.ORCID http://orcid.org/0000-0003-0819-5263
Yasunari HasedaUnited Immunity, Co., Ltd., Tokyo, 103-0022, Japan.
Takatoshi SogaUnited Immunity, Co., Ltd., Tokyo, 103-0022, Japan.
Hirokazu MatsushitaDivision of Translational Oncoimmunology, Aichi Cancer Center Research Institute, Nagoya, Japan.
Hiroaki IkedaDepartment of Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Kazunari AkiyoshiDepartment of Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Naozumi HaradaUnited Immunity, Co., Ltd., Tokyo, 103-0022, Japan.

Funding

Japan Agency for Medical Research and Development (AMED) JP20pc0101048Japan Agency for Medical Research and Development (AMED) JP21wm0125006Japan Agency for Medical Research and Development (AMED) JP223fa627001
6 · The paper itself

Abstract

Vaccine-induced T cells and neutralizing antibodies are essential for protection against SARS-CoV-2. Previously, we demonstrated that an antigen delivery system, pullulan nanogel (PNG), delivers vaccine antigen to lymph node medullary macrophages and thereby enhances the induction of specific CD8

Identifiers

PMID39294173
PMCPMC11411095

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.