Evidence map›Paper›PMID 39294363›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Paediatric low-grade glioma: the role of classical pathology in integrated diagnostic practice.

Thomas J Stone, Ashirwad Merve, Fernanda Valerio, Shireena A Yasin, Thomas S Jacques

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas J StoneDevelopmental Biology and Cancer Research and Teaching Department, UCL GOS Institute of Child Health, London, UK.ORCID 0000-0003-1394-8573
Ashirwad MerveDevelopmental Biology and Cancer Research and Teaching Department, UCL GOS Institute of Child Health, London, UK.ORCID 0000-0001-9715-1849
Fernanda ValerioDepartment of Histopathology, Great Ormond Street Hospital, London, UK.ORCID 0000-0001-5248-7314
Shireena A YasinDevelopmental Biology and Cancer Research and Teaching Department, UCL GOS Institute of Child Health, London, UK.ORCID 0009-0002-3012-2001
Thomas S JacquesDevelopmental Biology and Cancer Research and Teaching Department, UCL GOS Institute of Child Health, London, UK. t.jacques@ucl.ac.uk.ORCID 0000-0002-7833-2158

Funding

Brain Tumour Charity GN-000707
6 · The paper itself

Abstract

Low-grade gliomas are a cause of severe and often life-long disability in children. Pathology plays a key role in their management by establishing the diagnosis, excluding malignant alternatives, predicting outcomes and identifying targetable genetic alterations. Molecular diagnosis has reshaped the terrain of pathology, raising the question of what part traditional histology plays. In this review, we consider the classification and pathological diagnosis of low-grade gliomas and glioneuronal tumours in children by traditional histopathology enhanced by the opportunities afforded by access to comprehensive genetic and epigenetic characterisation.

Indexed as

Brain NeoplasmsGliomaChildHumansGliomaMAP kinaseNervous system neoplasmsNeuropathology

Identifiers

PMID39294363
PMCPMC11511714

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.