Evidence map›Paper›PMID 39294375›Full record

ArticleNature2024

Commensal consortia decolonize Enterobacteriaceae via ecological control.

Munehiro Furuichi, Takaaki Kawaguchi, Marie-Madlen Pust, Keiko Yasuma-Mitobe, Damian R Plichta, Naomi Hasegawa, Takashi Ohya, Shakti K Bhattarai, Satoshi Sasajima, Yoshimasa Aoto and 24 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Gut microbiota in health and disease.Molecular biomedicine · 2026
    Review
  10. Review
  11. Review
  12. Article
  13. Harnessing the microbiome for cancer therapy.Nature reviews. Microbiology · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors.

Munehiro Furuichi *Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-7742-1135
Takaaki Kawaguchi *Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-3354-961X
Marie-Madlen Pust *Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Keiko Yasuma-Mitobe *Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-7102-987X
Damian R PlichtaInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-6555-2557
Naomi HasegawaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Takashi OhyaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Shakti K BhattaraiDepartment of Microbiology and Physiological Systems, Program in Microbiome Dynamics, UMass Chan Medical School, Worcester, MA, USA.
Satoshi SasajimaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Yoshimasa AotoJSR-Keio University Medical and Chemical Innovation Center, Keio University School of Medicine, Tokyo, Japan.
Timur TuganbaevDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Mizuki YaginumaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Masahiro UedaRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID 0000-0001-8814-7071
Nobuyuki OkahashiRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID 0000-0001-9582-355X
Kimiko AmafujiJSR-Keio University Medical and Chemical Innovation Center, Keio University School of Medicine, Tokyo, Japan.
Yuko KiridoshiJSR-Keio University Medical and Chemical Innovation Center, Keio University School of Medicine, Tokyo, Japan.
Kayoko SugitaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
Martin StražarInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-3064-1055
Julian Avila-PachecoInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-9388-3946
Kerry PierceInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Clary B ClishInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-8259-9245
Ashwin N SkellyDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-1565-3376
Masahira HattoriRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Nobuhiro NakamotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-5203-7444
Silvia CaballeroVedanta Biosciences, Cambridge, MA, USA.
Jason M NormanVedanta Biosciences, Cambridge, MA, USA.ORCID 0000-0001-5049-8415
Bernat OlleVedanta Biosciences, Cambridge, MA, USA.
Takeshi TanoueDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-3639-8834
Wataru SudaRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Makoto AritaRIKEN Center for Integrative Medical Sciences, Yokohama, Japan.ORCID 0000-0001-9902-0463
Vanni BucciDepartment of Microbiology and Physiological Systems, Program in Microbiome Dynamics, UMass Chan Medical School, Worcester, MA, USA.ORCID 0000-0002-3257-2922
Koji AtarashiDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-5422-0736
Ramnik J XavierInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA. xavier@molbio.mgh.harvard.edu.ORCID 0000-0002-5630-5167
Kenya HondaDepartment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan. kenya@keio.jp.ORCID 0000-0001-8937-9835

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
Determinants of inception of inflammation in inflammatory bowel diseasesR01DK127171 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI ANANTHAKRISHNAN, ASHWIN N, XAVIER, RAMNIK J · 2021 to 2025
$5.4M
Identification and Characterization of Microbial Metabolites in ImmunityR01AI172147 · NIAID · BROAD INSTITUTE, INC. · PI Daniel Bartholomew Graham, Ramnik J Xavier · 2022 to 2026
$3.9M
Cardiovascular disease, metabolic syndrome, microbes and metabolites in FHSR01HL157717 · NHLBI · BROAD INSTITUTE, INC. · PI XAVIER, RAMNIK J · 2022 to 2025
$3.9M
NHLBI NIH HHS R01 HL157717NIAID NIH HHS R01 AI172147NIDDK NIH HHS P30 DK043351NIDDK NIH HHS R01 DK127171
6 · The paper itself

Abstract

Persistent colonization and outgrowth of potentially pathogenic organisms in the intestine can result from long-term antibiotic use or inflammatory conditions, and may perpetuate dysregulated immunity and tissue damage

Indexed as

EnterobacteriaceaeEnterobacteriaceae InfectionsGastrointestinal MicrobiomeSymbiosisAnimalsDrug Resistance, BacterialEscherichiaFecesGluconatesHumansInflammationIntestinesKlebsiellaMiceMice, Inbred C57BLProbioticsGluconatesgluconic acid

Identifiers

PMID39294375
PMCPMC11424487

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.