Evidence map›Paper›PMID 39294512›Full record

ReviewMolecular biotechnology2025

PerR: A Peroxide Sensor Eliciting Metal Ion-dependent Regulation in Various Bacteria.

Divya Kandari, Hemant Joshi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Divya KandariSchool of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
Hemant JoshiSchool of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India. hemant17_sbt@jnu.ac.in.ORCID http://orcid.org/0000-0002-6469-2814

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria have to thrive in difficult conditions wherein their competitors generate partially reduced forms of oxygen, like hydrogen peroxide and superoxides. These oxidative stress molecules can also arise from within via the autoxidation of redox enzymes. To adapt to such conditions, bacteria express detox enzymes as well as repair proteins. Transcription factors regulate these defenses, and PerR is one of them. PerR is a Fur family transcriptional regulator that senses peroxide stress. Metal-bound PerR (either Mn

Indexed as

BacteriaBacterial ProteinsMetalsPeroxidesRepressor ProteinsGene Expression Regulation, BacterialHydrogen PeroxideIronOxidative StressBacterial ProteinsHydrogen PeroxideIronMetalsperoxide repressor proteinsPeroxidesRepressor ProteinsMetalloregulatorOxidative stressPathogenic bacteriaTranscription factorVirulence

Identifiers

PMID39294512

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.