ReviewNeurobiology of stress2024
Effects of chronic stress on cognitive function - From neurobiology to intervention.
Review in Neurobiology of stress, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Performance of artificial intelligence models for monitoring psychological stress using noncontact physiological signals: a systematic review and meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Acute Stress Impacts Executive-Social Function: Evidence From Prefrontal Activation and fNIRS-Based Hyperscanning.Brain and behavior · 2026Trial
- A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.Frontiers in nutrition · 2026Trial
- Network activation and its association with perceived stress underlie performance under stressful high demand.Neurobiology of stress · 2026Article
- Associations of Social Support, Loneliness, and Physical Activity with Cognitive Function in Older Adults with Mild Cognitive Impairment.Journal of clinical medicine · 2026Article
- Chronic stress, social support, and domain-specific cognitive decline in HABS-HD.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Article
- Instrumental Reminiscence and Coping Strategies in Older Adults Exposed to Armed Conflict in Colombia.Stress and health : journal of the International Society for the Investigation of Stress · 2026Article
- Prevalence of Post-Traumatic Stress Injuries Among Canadian Public Safety Communicators: A Nationwide Comparative Study: Prévalence des blessures de stress post-traumatique chez les communicateurs en sécurité publique canadiens : étude comparative nationale.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2026Article
- Income Volatility During Early to Mid-adulthood and 10-year Memory Decline in a Longitudinal Synthetic Cohort.Epidemiology (Cambridge, Mass.) · 2026Article
- The mediating role of mental fatigue awareness in the relationship between perceived stress and psychological well-being among combat athletes.BMC psychology · 2026Article
- Lower breathing frequencies in personalized slow-paced breathing enhance relaxation and reduce arousal.iScience · 2026Article
- TGR5 is essential for protecting from chronic stress-induced learning and memory impairments in mice by modulating inflammation associated with the gut-brain axis.Journal of neuroinflammation · 2026Article
- Social vulnerability shapes deep clinical phenotypes and brain health in aging and dementia across Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- A Systematic Review of Functional Brain Imaging Studies in Neurofibromatosis 1.Neuropsychology review · 2026Review
- Physical Activity and Clinically Defined Arterial Hypertension in Consecutive Primary Care Patients: A Real-World Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Adolescent Stress Exposure: Behavioral Consequences and Molecular Mechanisms in Corticolimbic Networks.bioRxiv : the preprint server for biology · 2026Article
- Multiplexed changes in synaptic transmission underlie stress-induced reduction of persistent firing in the parietal cortex.Progress in neurobiology · 2026Article
- Homocysteine Drives Hippocampal Blood-Brain Barrier Disruption and Cognitive Decline Under Chronic Stress via DNA Hypomethylation of Cav1.2.Brain sciences · 2026Article
- Targeting insulo-frontal pathway to reduce stress-evoked cognitive rigidity.Nature communications · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Exposure to chronic stress contributes considerably to the development of cognitive impairments in psychiatric disorders such as depression, generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and addictive behavior. Unfortunately, unlike mood-related symptoms, cognitive impairments are not effectively treated by available therapies, a situation in part resulting from a still incomplete knowledge of the neurobiological substrates that underly cognitive domains and the difficulty in generating interventions that are both efficacious and safe. In this review, we will present an overview of the cognitive domains affected by stress with a specific focus on cognitive flexibility, behavioral inhibition, and working memory. We will then consider the effects of stress on neuronal correlates of cognitive function and the factors which may modulate the interaction of stress and cognition. Finally, we will discuss intervention strategies for treatment of stress-related disorders and gaps in knowledge with emerging new treatments under development. Understanding how cognitive impairment occurs during exposure to chronic stress is crucial to make progress towards the development of new and effective therapeutic approaches.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.