Evidence map›Paper›PMID 39300055›Full record

ArticleEuropean geriatric medicine2024

Performance of the SARC-F, SARC-CalF, and calf circumference for sarcopenia case finding in community-dwelling older adults.

Hanna Kerminen, Satu Jyväkorpi, Annele Urtamo, Heini Huhtala, Hanna Öhman, Riccardo Calvani, Emanuele Marzetti, Kaisu Pitkälä, Timo Strandberg

Registry-linked trialAbstract read
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In one paragraph

Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02582138 (Sarcopenia and Physical fRailty IN Older People), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02582138 naunknown statusnot on this map

Sarcopenia and Physical fRailty IN Older People: Multi-componenT Treatment Strategies (SPRINTT)

TypeinterventionalSponsorCatholic University of the Sacred HeartRan2016 to 2018Enrolled1,500ConditionsSarcopeniaArmsMulticomponent intervention (MCI), Healthy Aging Lifestyle Education (HALE)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The sarcopenia-pain connection: why mechanisms matter for patient care?Frontiers in pain research (Lausanne, Switzerland) · 2026
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hanna KerminenFaculty of Medicine and Health Technology, The Gerontology Research Center (GEREC), Tampere University, Arvo Ylpön Katu 34, 33520, Tampere, Finland. hanna.kerminen@tuni.fi.ORCID 0000-0002-7483-8725
Satu JyväkorpiThe National Nutrition Council of Finland, Helsinki, Finland.
Annele UrtamoDepartment of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.
Heini HuhtalaFaculty of Social Sciences, Tampere University, Tampere, Finland.
Hanna ÖhmanDepartment of Geriatric Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Riccardo CalvaniDepartment of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Emanuele MarzettiDepartment of Geriatrics, Orthopedics and Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy.
Kaisu PitkäläDepartment of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.
Timo StrandbergDepartment of Geriatric Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Funding

Juho Vainion Säätiö 202400269Suomen Lääketieteen Säätiö 6554Yrjö Jahnssonin Säätiö 20237722
6 · The paper itself

Abstract

purposeWe compared the performance of SARC-F, SARC-CalF, calf circumference (CC), and body mass index (BMI)-adjusted CC for sarcopenia case-finding in community-dwelling older adults.

methodsData of Finnish participants (women/men n = 192/36, mean age (SD) of 76.9 (4.8) years) recruited in the SPRINTT trial (NCT02582138) were used. Sarcopenia was determined as a combination of low muscle function (chair-stand-test) and low appendicular lean mass (ALM) detected by whole-body dual-energy X-ray absorptiometry. Associations of case-finding tools with sarcopenia were analysed using ROC curves and logistic regression.

resultsThe rates of probable and confirmed sarcopenia were 95% and 18% in women and 94% and 36% in men, respectively. Performance of CC for sarcopenia (women AUC 0.85 [95% CI 0.78-0.92]/ men 0.85 [95% CI 0.71-1.0]) was superior to that of other tools; (AUC in women/men for SARC-F was 0.57/0.50, for SARC-CalF 0.76/0.79, and for BMI-adjusted CC 0.68/0.66). The best performance was found for a CC cut-off point of ≤ 34 cm in women with sensitivity/specificity 82.4/75.3% and ≤ 36 cm in men with sensitivity/specificity 76.9/87.0%. For each cm decrease in CC, adjusted for age and BMI, there was a 30% increase in the odds of sarcopenia in women (OR 1.30, 95% CI 1.09─1.56). Although there was a similar pattern in men, the results did not reach statistical significance (OR 1.34, 95% CI 0.84- 2.14).

conclusionsCC was superior to other tools for sarcopenia case-finding. The best performance was found for a CC cut-off point of ≤ 34 cm in women and ≤ 36 cm in men.

Indexed as

Absorptiometry, PhotonBody Mass IndexSarcopeniaAgedAged, 80 and overBody CompositionClinical Studies as TopicFemaleFinlandGeriatric AssessmentHumansLegMaleMuscle, SkeletalROC CurveAnthropometryCase-findingOlder peopleSarcopeniaScreeningSensitivity and specificitySkeletal muscle

Identifiers

PMID39300055
PMCPMC11631994

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.