Evidence map›Paper›PMID 39300399›Full record

SynthesisBMC women's health2024

Understanding the impact of endometriosis on women's life: an integrative review of systematic reviews.

Tilektes Maulenkul, Alina Kuandyk, Dinara Makhadiyeva, Anar Dautova, Milan Terzic, Ainash Oshibayeva, Ikilas Moldaliyev, Ardak Ayazbekov, Talgat Maimakov, Yerbolat Saruarov and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in BMC women's health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Review
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  6. Patient-Centred Perspectives on Diagnostic Strategies for Endometriosis: A Qualitative Study.BJOG : an international journal of obstetrics and gynaecology · 2026
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  16. Observational
  17. Sexual and reproductive health matters · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tilektes MaulenkulDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan.
Alina KuandykDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan.
Dinara MakhadiyevaDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan.
Anar DautovaDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan.
Milan TerzicDepartment of Surgery, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan.
Ainash OshibayevaKhoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan.
Ikilas MoldaliyevKhoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan.
Ardak AyazbekovKhoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan.
Talgat MaimakovKhoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan.
Yerbolat SaruarovKhoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan.
Faye FosterDepartment of Medicine, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan.
Antonio Sarria-SantameraDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana, 010000, Kazakhstan. antonio.sarria@nu.edu.kz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometriosis is a challenging chronic condition with a significant impact on women's well-being. This systematic review of systematic reviews aims to assess the evidence investigating the intricate interplay between endometriosis and quality of life (QoL).

methodsA systematic review was performed for English-language studies up to January 2022 to identify systematic reviews with and without meta-analysis analyzing quantitative or qualitative data The following databases were searched: Scopus, PubMed, Embase, Web of Science and Cochrane Central Register of Controlled Trials. Participants/population were women with endometriosis, and the outcomes included were all reported outcomes evaluating the impact of endometriosis on women's QoL (PROSPERO 2021 CRD42021289347).

results15 systematic reviews were identified. 8 included meta-analysis: 4 explored the prevalence of mental health problems, and 1 analyzed, respectively, the overall impact of endometriosis, headache migraine, and sexual function. 7 articles reported on the mental consequences, and three sexual functioning. One was a qualitative review. The impact of the relationships with the healthcare system was analyzed in 3 reviews. Pain is a hallmark of endometriosis. Infertility and sexual problems are also frequent. Depression, anxiety, and stress represent significant contributors to lessening women's QoL. Women have frustrating relationships with the healthcare system: the complex and long diagnostic process, lack of treatment effectiveness, and persistence of symptoms contribute to emotional challenges. Negative cognitive patterns developed by women with emotional distress, such as catastrophizing and fear-avoidance behaviors, amplify the experience of pain.

conclusionThe limitations of this review are the high degree of heterogeneity of papers that include many factors, including comorbidities, and use of medical care that may impact QoL, and that most of them were cross-sectional. Endometriosis is a chronic disease that significantly impacts all domains of women's lifes. Pain, infertility, and stress linked with depression, and anxiety significantly influence QoL. Women are dissatisfied with the care they receive.

Indexed as

EndometriosisQuality of LifeFemaleHumansSystematic Reviews as TopicEndometriosisInfertilityMental healthPelvic painQuality of lifeSexual lifeSocial wellbeing

Identifiers

PMID39300399
PMCPMC11411992

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.