Evidence map›Paper›PMID 39301263›Full record

ArticleResearch (Washington, D.C.)2024

Amino Turbo Chirality and Its Asymmetric Control.

Ting Xu, Yu Wang, Shengzhou Jin, Anis U Rahman, Xianghua Yan, Qingkai Yuan, Hao Liu, Jia-Yin Wang, Wenxin Yan, Yinchun Jiao and 2 more

Abstract read
In one paragraph

Article in Research (Washington, D.C.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ting XuSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Yu WangSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Shengzhou JinSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Anis U RahmanDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA.
Xianghua YanDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA.
Qingkai YuanDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA.
Hao LiuDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA.
Jia-Yin WangSchool of Pharmacy, Continuous Flow Engineering Laboratory of National Petroleum and Chemical Industry, Changzhou University, Changzhou, Jiangsu 213164, China.
Wenxin YanSchool of Chemistry and Chemical Engineering, Key Laboratory of Theoretical Organic Chemistry and Functional Molecular, Ministry of Education, Hunan University of Science and Technology, Xiangtan, Hunan 411201, China.
Yinchun JiaoSchool of Chemistry and Chemical Engineering, Key Laboratory of Theoretical Organic Chemistry and Functional Molecular, Ministry of Education, Hunan University of Science and Technology, Xiangtan, Hunan 411201, China.
Ruibin LiangDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA.ORCID https://orcid.org/0000-0001-8741-1520
Guigen LiSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.ORCID https://orcid.org/0000-0002-9312-412X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of new targets containing 3 chiral elements of central, orientational, and turbo chirality have been designed and synthesized asymmetrically. The absolute configurations and conformations of these types of chirality were concurrently controlled by using chiral sulfonimine auxiliary and unambiguously determined by x-ray diffraction analysis. These targets include alpha unnatural amino acid derivatives, which may play an important role for drug design, discovery, and development. Three propellers of turbo framework are covalently connected to a chiral C(sp

Identifiers

PMID39301263
PMCPMC11411161

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.