Evidence map›Paper›PMID 39301929›Full record

ArticleFuture medicinal chemistry2024

Preclinical characterization of a water-soluble low-impact ampakine prodrug, CX1942 and its active moiety, CX1763.

Daniel P Radin, Sheng Zhong, Rok Cerne, Mohammed Shoaib, Jeffrey M Witkin, Arnold Lippa

Abstract read
In one paragraph

Article in Future medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel P RadinRespireRx Pharmaceuticals Inc., 126 Valley Road, Glen Rock, NJ 07452, USA.ORCID 0000-0003-3775-7712
Sheng ZhongPsychogenics, 215 College Road, Paramus, NJ 07652, USA.
Rok CerneRespireRx Pharmaceuticals Inc., 126 Valley Road, Glen Rock, NJ 07452, USA.
Mohammed ShoaibSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
Jeffrey M WitkinRespireRx Pharmaceuticals Inc., 126 Valley Road, Glen Rock, NJ 07452, USA.
Arnold LippaRespireRx Pharmaceuticals Inc., 126 Valley Road, Glen Rock, NJ 07452, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ProdrugsSolubilityWaterAnimalsMaleMiceRatsRats, Sprague-DawleyReceptors, AMPAProdrugsReceptors, AMPAWaterADHDampakineAMPA receptordrug developmentdrug discoverydrug metabolismlocomotor activityneurological therapeuticsopioid-induced respiratory depressionpharmacology

Identifiers

PMID39301929
PMCPMC11622767

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.