Evidence map›Paper›PMID 39302131›Full record

ArticlemBio2024

The GPI sidechain of

Julia A Alvarez, Elisabet Gas-Pascual, Sahil Malhi, Juan C Sánchez-Arcila, Ferdinand Ngale Njume, Hanke van der Wel, Yanlin Zhao, Laura García-López, Gabriella Ceron, Jasmine Posada and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Bioactive materials · 2025
    Article
  2. Free GPIs and Comparison of GPI Structures Among Species.International journal of molecular sciences · 2025
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Julia A AlvarezDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
Elisabet Gas-PascualDepartment of Biochemistry and Molecular Biology, Center for Tropical and Emerging Global Diseases, and Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Sahil MalhiDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
Juan C Sánchez-ArcilaDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
Ferdinand Ngale NjumeDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
Hanke van der WelDepartment of Biochemistry and Molecular Biology, Center for Tropical and Emerging Global Diseases, and Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Yanlin ZhaoDepartment of Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA.ORCID 0000-0002-0278-7543
Laura García-LópezDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
Gabriella CeronDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
Jasmine PosadaDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
Scott P SouzaDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.
George S YapDepartment of Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA.ORCID 0000-0003-4814-8445
Christopher M WestDepartment of Biochemistry and Molecular Biology, Center for Tropical and Emerging Global Diseases, and Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.ORCID 0000-0001-9077-965X
Kirk D C JensenDepartment of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.ORCID 0000-0003-0707-964X

Funding

New requirements for immunity to parasitic pathogens - when vaccines work and why they failR01AI137126 · NIAID · UNIVERSITY OF CALIFORNIA, MERCED · PI JENSEN, KIRK DAVID CHRISTIAN · 2018 to 2022
$2.0M
Enabling tools for protists pathogen glycobiologyR21AI123161 · NIAID · UNIVERSITY OF GEORGIA · PI TARLETON, RICK L, WELLS, LANCE · 2015 to 2016
$745k
Targeting Conserved Molecular and Structural Features of Apicomplexans Towards a Rational Vaccine DesignR21AI176186 · NIAID · UNIVERSITY OF CALIFORNIA, MERCED · PI JENSEN, KIRK DAVID CHRISTIAN · 2024 to 2025
$457k
GDF-15 as a mediator of immune-regulated sickness response during infectionR21AI171670 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI YAP, GEORGE S. · 2023 to 2024
$417k
HHS | NIH | OSC | Common Fund (NIH Common Fund) 1R01AI137126,1R21AI176186HHS | NIH | OSC | Common Fund (NIH Common Fund) 1R21AI123161HHS | NIH | OSC | Common Fund (NIH Common Fund) 1R21AI171670NIAID NIH HHS R01 AI137126NIAID NIH HHS R21 AI123161NIAID NIH HHS R21 AI171670NIAID NIH HHS R21 AI176186
6 · The paper itself

Abstract

Glycosylphosphatidylinositols (GPIs) are highly conserved anchors for eukaryotic cell surface proteins. The apicomplexan parasite,

Indexed as

GlycosylphosphatidylinositolsToxoplasmaAnimalsFemaleGlycosyltransferasesMiceMice, Inbred C57BLMice, KnockoutProtozoan ProteinsToxoplasmosisVirulenceGlycosylphosphatidylinositolsGlycosyltransferasesProtozoan ProteinsCD36galectin-3GIPLGPIGPI sidechainmacrophagesmass spectrometrypathogenesisPIGEPIGJsurface antigensToxoplasma gondii

Identifiers

PMID39302131
PMCPMC11481522

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.