Evidence map›Paper›PMID 39303682›Full record

ArticleCell2024

Virology-The next fifty years.

Edward C Holmes, Florian Krammer, Felicia D Goodrum

Abstract readHistorical Article
In one paragraph

Article in Cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Editorial: Genetic and molecular markers in human viral infections.Frontiers in cellular and infection microbiology · 2026
    Article
  3. Protein Language Models in Virology: A Review of Advances and Applications.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Artificial intelligence for disease X: Progress and challenges.Journal of translational internal medicine · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Edward C HolmesSchool of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia; Laboratory of Data Discovery for Health Limited, Hong Kong SAR, China. Electronic address: edward.holmes@sydney.edu.au.
Florian KrammerDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna, Vienna, Austria.
Felicia D GoodrumDepartment of Immunobiology, BIO5 Institute, University of Arizona, Tucson, AZ, USA.

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI BRISCOE, LYNN · 2019 to 2025
$3932.6M
COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTER: UNIVERSAL INFLUENZA VACCINE RESEARCH75N93019C00051 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2019 to 2025
$105.4M
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00014 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GARCIA-SASTRE, ADOLFO · 2021 to 2025
$62.6M
Household Respiratory Virus SARS-CoV-2 Transmission and Immunity Sub-Study (HRTS)U01AI144616 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI GORDON, AUBREE L, THOMAS, PAUL G. · 2019 to 2025
$43.7M
The Administrative CoreP01AI127335 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI JAY A NELSON · 2017 to 2026
$24.6M
DEVELOPMENT OF A VACCINE CANDIDATE FOR CORONAVIRUSES75N93023C00019 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2023 to 2023
$15.9M
Evaluating Modes of Influenza Transmission using a Randomized Controlled Trial (EMIT-2-RCT)U19AI162130 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI SREBRIC, JELENA · 2021 to 2025
$15.2M
Viral Immunity and VAccination (VIVA) Human Immunology Project Consortium (HIPC)U19AI168631 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ana Fernandez-Sesma · 2022 to 2026
$14.4M
Understanding antibody responses and defining correlates of protection for endemic and pandemic coronavirus strainsP01AI172531 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ali Hassan Ellebedy, Viviana A Simon · 2023 to 2026
$12.5M
Vulnerability of SARS- CoV-2 Infection in Lung Cancer Based on Serological Antibody AnalysesU54CA260560 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SHYR, YU · 2020 to 2024
$10.0M
Immunobiology of Influenza Virus-related Critical Illness in Young HostsR01AI154470 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI RANDOLPH, ADRIENNE G, THOMAS, PAUL G. · 2020 to 2024
$4.7M
Mechanisms of Human Cytomegalovirus Latency in Primary Human Hematopoietic CellsR37AI079059 · NIAID · UNIVERSITY OF ARIZONA · PI Felicia D Goodrum · 2019 to 2026
$3.3M
NCI NIH HHS 75N91019D00024NCI NIH HHS U54 CA260560NIAID NIH HHS 75N93019C00051NIAID NIH HHS 75N93021C00014NIAID NIH HHS 75N93023C00019NIAID NIH HHS P01 AI127335NIAID NIH HHS P01 AI172531NIAID NIH HHS R01 AI154470NIAID NIH HHS R01 AI169728NIAID NIH HHS R01 AI177392NIAID NIH HHS R37 AI079059NIAID NIH HHS U01 AI144616NIAID NIH HHS U19 AI162130NIAID NIH HHS U19 AI168631NIGMS NIH HHS R25 GM150146
6 · The paper itself

Abstract

Virology has made enormous advances in the last 50 years but has never faced such scrutiny as it does today. Herein, we outline some of the major advances made in virology during this period, particularly in light of the COVID-19 pandemic, and suggest some areas that may be of research importance in the next 50 years. We focus on several linked themes: cataloging the genomic and phenotypic diversity of the virosphere; understanding disease emergence; future directions in viral disease therapies, vaccines, and interventions; host-virus interactions; the role of viruses in chronic diseases; and viruses as tools for cell biology. We highlight the challenges that virology will face moving forward-not just the scientific and technical but also the social and political. Although there are inherent limitations in trying to outline the virology of the future, we hope this article will help inspire the next generation of virologists.

Indexed as

COVID-19VirologyHistory, 21st CenturyHost-Pathogen InteractionsHumansPandemicsSARS-CoV-2Virus DiseasesVirusescancerchronic diseaseco-infectiontherapiesvaccinesvirologyvirosphere

Identifiers

PMID39303682
PMCPMC11467463

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.