Evidence map›Paper›PMID 39304992›Full record

ArticleTransfusion2024

Racial and ethnic differences in transfusion rates in adolescent scoliosis surgery: Preoperative anemia as a mediator of disparity.

Sophie Fisher, Stanford Chihuri, Jean Guglielminotti, Guohua Li, Lisa Eisler

Abstract readMulticenter Study
In one paragraph

Article in Transfusion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sophie FisherColumbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.ORCID 0000-0002-6771-6113
Stanford ChihuriDepartment of Anesthesiology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Jean GuglielminottiDepartment of Anesthesiology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Guohua LiDepartment of Anesthesiology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Lisa EislerDepartment of Anesthesiology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.ORCID 0000-0001-9726-2354

Funding

Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6M
Reducing Racial and Ethnic Disparities in Maternal Health through Policy InterventionsR01MD018410 · NIMHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jean R Guglielminotti · 2023 to 2026
$1.6M
Training Medical Students in NIDDK ResearchT35DK093430 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI QAIS AL-AWQATI, Utpal Pajvani · 2012 to 2026
$1.3M
Efficacy of Preoperative Oral Iron Supplementation in Adolescents Undergoing Scoliosis SurgeryK23GM152933 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Lisa Danielle Eisler · 2023 to 2026
$771k
National Institute of General Medical Sciences and the National Center for Advancing Translational Sciences, National Institutes of Health K23GM152933National Institute of General Medical Sciences and the National Center for Advancing Translational Sciences, National Institutes of Health KL2TR001874NIDDK NIH HHS T35DK093430NIGMS NIH HHS K23 GM152933NIMHD NIH HHS R01MD018410
6 · The paper itself

Abstract

backgroundPediatric patients from minoritized racial and ethnic groups receive red blood cell (RBC) transfusions more frequently while undergoing major surgical procedures. Our objective was to identify the contribution of preoperative anemia to racial and ethnic differences in RBC transfusion rates in adolescent spine surgery. STUDY DESIGN AND

methodsThis is a multicenter, retrospective cohort study of the National Surgical Quality Improvement Program Pediatric database, 2016 to 2021 for patients in the United States and Canada.

resultsAdolescents identifying as non-Hispanic Black, Hispanic, and other race/ethnicity presented with higher rates of preoperative anemia than non-Hispanic White adolescents (16.3%, 10.6%, and 9.9%, vs. 7.8%, respectively; p < .0001) and were transfused at higher rates (14.4%, 11.9%, 16.5%, vs. 10.0%, respectively; p < .0001). Minoritized groups demonstrated higher adjusted odds of RBC transfusion compared with non-Hispanic Whites (non-Hispanic Black: aOR 1.45 95% CI 1.26-1.65, Hispanic: aOR 1.17 95% CI 0.96-1.41, other race/ethnicity: aOR 1.63 95% CI 1.26-2.09). Of the total effect of minoritized race and/or ethnicity on RBC transfusion, 13.9% was attributed to the indirect effect through preoperative anemia. DISCUSSION: In this cohort study, patients from minoritized racial and ethnic groups received RBC transfusions at a higher rate than non-Hispanic White patients, and the difference was partially mediated by preoperative anemia. Future efforts to minimize transfusions and improve health equity should target this modifiable risk factor alongside other sources of disparity and discrimination.

Indexed as

AnemiaErythrocyte TransfusionScoliosisAdolescentBlack or African AmericanBlood TransfusionCanadaChildEthnicityFemaleHealthcare DisparitiesHispanic or LatinoHumansMaleRetrospective StudiesUnited Statesanemiadisparityhealth equityminoritized patientspatient blood managementRBC transfusionscoliosisspinal fusion

Identifiers

PMID39304992
PMCPMC11573638

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.