Evidence mapPaperPMID 39308196Full record

ArticleThe British journal of nutrition2024

Interaction between genetic risk score and dietary fat intake on lipid-related traits in Brazilian young adults.

Ramatu Wuni, Heyam Amerah, Serena Ammache, Nathália T Cruvinel, Nara R da Silva, Gunter G C Kuhnle, Maria A Horst, Karani S Vimaleswaran

Abstract read
In one paragraph

Article in The British journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ramatu WuniHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research (ICMR), University of Reading, ReadingRG6 6DZ, UK.
Heyam AmerahHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research (ICMR), University of Reading, ReadingRG6 6DZ, UK.
Serena AmmacheHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research (ICMR), University of Reading, ReadingRG6 6DZ, UK.
Nathália T CruvinelNutritional Genomics Research Group, Faculty of Nutrition, Federal University of Goiás (UFG), Goiania, Brazil.
Nara R da SilvaNutritional Genomics Research Group, Faculty of Nutrition, Federal University of Goiás (UFG), Goiania, Brazil.
Gunter G C KuhnleHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research (ICMR), University of Reading, ReadingRG6 6DZ, UK.
Maria A HorstNutritional Genomics Research Group, Faculty of Nutrition, Federal University of Goiás (UFG), Goiania, Brazil.ORCID https://orcid.org/0000-0002-6249-8946
Karani S VimaleswaranHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research (ICMR), University of Reading, ReadingRG6 6DZ, UK.ORCID https://orcid.org/0000-0002-8485-8930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The occurrence of dyslipidaemia, which is an established risk factor for cardiovascular diseases, has been attributed to multiple factors including genetic and environmental factors. We used a genetic risk score (GRS) to assess the interactions between genetic variants and dietary factors on lipid-related traits in a cross-sectional study of 190 Brazilians (mean age: 21 ± 2 years). Dietary intake was assessed by a trained nutritionist using three 24-h dietary recalls. The high GRS was significantly associated with increased concentration of TAG (beta = 0·10 mg/dl, 95 % CI 0·05-0·16;

Indexed as

Cholesterol, HDLDietary FatsAdolescentAdultBrazilCardiovascular DiseasesCholesterol, LDLCross-Sectional StudiesDietDyslipidemiasFemaleGenetic Predisposition to DiseaseGenetic Risk ScoreHumansMalePolymorphism, Single NucleotideCholesterol, HDLCholesterol, LDLDietary FatsTriglyceridesBrazilFat intakeGenetic risk scoreSFATAG to HDL-cholesterol ratio

Identifiers

PMID39308196
PMCPMC11536265

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.