Evidence map›Paper›PMID 39308490›Full record

ArticleNuclear medicine and molecular imaging2024

Enhanced γ-H2AX Foci Frequency and Altered Gene Expression in Participants Exposed to Ionizing Radiation During I-131 Nuclear Medicine Procedures.

Shruti Hariharan, Smruthi Seethashankar, Nandhini Kannan, Sathesh Christopher, Aishwarya T A, Venkateswarlu Raavi, Venkatachalapathy Easwaramoorthy, Palani Murugaiyan, Venkatachalam Perumal

Abstract read
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In one paragraph

Article in Nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shruti Hariharan *Department of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, 600 116 Tamil Nadu India.
Smruthi Seethashankar *Department of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, 600 116 Tamil Nadu India.
Nandhini KannanDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, 600 116 Tamil Nadu India.
Sathesh ChristopherDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, 600 116 Tamil Nadu India.
Aishwarya T ADepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, 600 116 Tamil Nadu India.
Venkateswarlu RaaviDepartment of Cell Biology and Molecular Genetics, Sri Devaraj Urs Academy of Higher Education and Research (Deemed to be University), Kolar, 563 103 Karnataka India.
Venkatachalapathy EaswaramoorthyDepartment of Nuclear Medicine & PET/CT, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, 600 116 Tamil Nadu India.
Palani MurugaiyanDepartment of Nuclear Medicine & PET/CT, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, 600 116 Tamil Nadu India.
Venkatachalam PerumalDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, 600 116 Tamil Nadu India.ORCID 0000-0003-2152-2003

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Ionizing radiation-based technologies are extensively used in the diagnosis and treatment of diseases. While utilizing the technologies, exposure to a certain amount of radiation is unavoidable. Data can be obtained from participants who received radiation during medical imaging and therapeutic purposes to predict the effects of low-dose radiation. Methods: To understand the effects of low-dose radiation, participants ( Results: Mean frequency of γ-H2AX foci in pre-samples was 0.28 ± 0.16, and post-samples were 1.03 ± 0.60. γ-H2AX foci frequency obtained from post-samples showed significant ( Conclusion: The results of this study indicate that the participants who received I-131 (low doses of β- and γ-radiation) can produce substantial biological effects.

Indexed as

Chromosomal aberrationsGene expressionI-131Low doseγ-H2AX

Identifiers

PMID39308490
PMCPMC11415327

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.