ReviewFrontiers in physiology2024
The age-related effects on orthodontic tooth movement and the surrounding periodontal environment.
Review in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Randomized controlled trial comparing AI-assisted digital and conventional orthodontics: Superior PAR reduction and occlusal outcomes.PloS one · 2026Trial
- GDF15 modulates aging-associated adaptions in the mechanoresponse of periodontal ligament fibroblasts.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026Article
- Article
- Maxillary anterior retraction with clear aligner: a retrospective comparative cohort study of efficiency between periodontally healthy and stable periodontitis patients.Progress in orthodontics · 2026Article
- Bcl6 inhibits osteoclastogenesis by upregulating STAT1 phosphorylation.Molecular biology reports · 2026Article
- [Aging-Associated Oral Microbiota Dysbiosis and Hypofunction: Their Role in Alzheimer's Disease Pathogenesis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Review
- Tension-Dominant Orthodontic Loading and Buccal Periodontal Phenotype Preservation: An Integrative Mechanobiological Model Supported by FEM and a Proof-of-Concept CBCT.Journal of functional biomaterials · 2026Article
- External Root Resorption Associated with Orthodontic Treatment-Descriptive Correlations of Biological and Dental Risk Factors.Dentistry journal · 2026Article
- Micro-osteoperforations' impact on orthodontic tooth movement rate: Split mouth research.Bioinformation · 2026Article
- Conservative orthodontic re-treatment management of severely proclined upper anterior teeth with root resorption.Journal of orthodontic science · 2026Article
- Risk factors for proximal contact loss after implant-supported prosthetic restoration in adjacent natural teeth.BMC oral health · 2025Article
- Influence of sex and age on the gene expression of periodontal and pulp tissues during orthodontic tooth movement.Progress in orthodontics · 2025Article
- Determination of Osteocalcin Levels in Gingival Crevicular Fluid to Assess the Effectiveness of Laser Therapy in Patients with Orthodontic Treatment.Biomedicines · 2025Article
- Integrative multi-omics and causal inference reveal periodontal ligament cell-macrophage crosstalk under orthodontic force.Progress in orthodontics · 2025Article
- Recent Advances in the Role of Osteocytes in Orthodontic Tooth Movement.International journal of molecular sciences · 2025Review
- Identification of candidate immunity biomarkers associated with age-related variations in osteoclast activity in a mouse model of orthodontic tooth movement.BMC oral health · 2025Article
- Correlation of body mass index and alveolar bone dimensions in the maxilla using cone-beam computed tomography.BMC oral health · 2025Article
- Review
- The Interaction Between Orthodontics and Periodontal Tissue Remodeling :.Galen medical journal · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthodontic treatment in adults is often related to longer treatment time as well as higher periodontal risks compared to adolescents. The aim of this review is to explore the influence of age-related chages on orthodontic tooth movement (OTM) from macro and micro perspectives. Adults tend to show slower tooth movement speed compared to adolescence, especially during the early phase. Under orthodontic forces, the biological responses of the periodontal ligament (PDL) and alveolar bone is different between adult and adolescents. The adult PDL shows extended disorganization time, increased cell senescence, less cell signaling and a more inflammatory microenvironment than the adolescent PDL. In addition, the blood vessel surface area is reduced during the late movement phase, and fiber elasticity decreases. At the same time, adult alveolar bone shows a higher density, as well as a reduced osteoblast and osteoclast activation, under orthodontic forces. The local cytokine expression also differs between adults and adolescents. Side-effects, such as excessive root resorption, greater orthodontic pain, and reduced pulpal blood flow, also occur more frequently in adults than in adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.