Evidence map›Paper›PMID 39309016›Full record

ArticleGreen chemistry : an international journal and green chemistry resource : GC2024

Practical electrochemical hydrogenation of nitriles at the nickel foam cathode.

Rok Narobe, Marcel Nicolas Perner, María de Jesús Gálvez-Vázquez, Conrad Kuhwald, Martin Klein, Peter Broekmann, Sina Rösler, Bertram Cezanne, Siegfried R Waldvogel

Abstract read
In one paragraph

Article in Green chemistry : an international journal and green chemistry resource : GC, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Electrochemical Hydrogenation of Aza-Arenes Using HJournal of the American Chemical Society · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rok NarobeDepartment of Chemistry, Johannes Gutenberg University Mainz 55128 Mainz Germany.
Marcel Nicolas PernerDepartment of Chemistry, Johannes Gutenberg University Mainz 55128 Mainz Germany.ORCID https://orcid.org/0009-0002-3257-882X
María de Jesús Gálvez-VázquezDepartment of Chemistry, Johannes Gutenberg University Mainz 55128 Mainz Germany.ORCID https://orcid.org/0000-0002-0416-6556
Conrad KuhwaldSigma-Aldrich Production GmbH 9470 Buchs Switzerland.
Martin KleinMerck Electronics KGaA 64293 Darmstadt Germany.ORCID https://orcid.org/0000-0001-9512-4580
Peter BroekmannDepartment of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern 3012 Bern Switzerland.
Sina RöslerSigma-Aldrich Production GmbH 9470 Buchs Switzerland.
Bertram CezanneMerck Electronics KGaA 64293 Darmstadt Germany.ORCID https://orcid.org/0000-0001-9633-7166
Siegfried R WaldvogelDepartment of Chemistry, Johannes Gutenberg University Mainz 55128 Mainz Germany.ORCID https://orcid.org/0000-0002-7949-9638

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a scalable hydrogenation method for nitriles based on cost-effective materials in a very simple two-electrode setup under galvanostatic conditions. All components are commercially and readily available. The method is very easy to conduct and applicable to a variety of nitrile substrates, leading exclusively to primary amine products in yields of up to 89% using an easy work-up protocol. Importantly, this method is readily transferable from the milligram scale in batch-type screening cells to the multi-gram scale in a flow-type electrolyser. The transfer to flow electrolysis enabled us to achieve a notable 20 g day

Identifiers

PMID39309016
PMCPMC11413620

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.