Evidence mapPaperPMID 39309662Full record

ArticleJACC. Advances2024

Impact of Guideline-Directed Statin Prescriptions on Cardiovascular Outcomes by Race in a Real-World Primary Prevention Cohort.

Eli J Hay, Jianhui Zhu, Floyd W Thoma, Oscar C Marroquin, Pallavi Muluk, Malamo E Countouris, Anson J Smith, Gul J Saeed, Mahmoud Al Rifai, Amber E Johnson and 2 more

Abstract read
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Electronic Health Record Alerts to Improve Lipid Lowering After a Recent Myocardial Infarction.Journal of the American Heart Association · 2026 · on this map
    Observational
  2. Article
  3. Population-Level Gaps in Coronary Artery Disease Care: A Focused Review.Methodist DeBakey cardiovascular journal · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eli J HayUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.
Jianhui ZhuUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.
Floyd W ThomaUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.
Oscar C MarroquinUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.
Pallavi MulukUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.
Malamo E CountourisUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.
Anson J SmithUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.
Gul J SaeedRoger Williams Medical Center, Department of Internal Medicine, Providence, Rhode Island, USA.
Mahmoud Al RifaiHouston Methodist Academic Institute, DeBakey Heart & Vascular Center, Houston, Texas, USA.
Amber E JohnsonUniversity of Chicago Medicine, Department of Medicine and Section of Cardiology, Chicago, Illinois, USA.
Anum SaeedUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.
Suresh R MulukutlaUniversity of Pittsburgh Medical Center (UPMC) Department of Medicine, Division of Cardiology, Pittsburgh, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Data on real-world statin prescription in large, private health care networks and impacts on primary prevention of atherosclerotic cardiovascular disease (ASCVD) outcomes across race are scarce. Objectives: The purpose of this study was to investigate the impact of statin prescription on ASCVD outcomes within and across race in a large, nongovernmental health care system. Methods: Statin prescription in Black and White patients without ASCVD was evaluated (2013-2019). Guideline-directed statin intensity was defined as at least "moderate" for intermediate and high-risk patients. Statin prescription at index and ASCVD outcomes at follow-up (myocardial infarction/revascularization, stroke, mortality) were assessed via electronic health care records using International Classification of Diseases-9 and 10 codes. Cox regression models, adjusted for CVD risk factors, were used to calculate HRs for association between statin prescription and incident ASCVD events across race. Results: Among 270,079 patients, 7.6% (n = 20,477) and 92.4% (n = 249,602) identified as Black and White, respectively. Significantly fewer Black patients were prescribed statin therapy than White patients (13.6% vs 19.0%; Conclusions: Statins remain underprescribed. Although Black patients received proportionally less statin prescription than White patients, this was not associated with higher risk of mortality in Black patients.

Indexed as

ASCVDguidelinespreventionracestatins

Identifiers

PMID39309662
PMCPMC11414661

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.