Evidence map›Paper›PMID 39312647›Full record

ArticleGut microbes

EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases.

Ipsita Nandi, Rachana Pattani Ramachandran, Deborah E Shalev, Dina Schneidman-Duhovny, Raisa Shtuhin-Rahav, Naomi Melamed-Book, Efrat Zlotkin-Rivkin, Alexander Rouvinski, Ilan Rosenshine, Benjamin Aroeti

Abstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ipsita NandiDepartment of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, The Edmond J. Safra Campus - Givat Ram, Jerusalem, Israel.ORCID 0000-0002-4502-2559
Rachana Pattani RamachandranDepartment of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, The Edmond J. Safra Campus - Givat Ram, Jerusalem, Israel.ORCID 0000-0002-4448-5906
Deborah E ShalevThe Wolfson Centre for Applied Structural Biology, The Hebrew University of Jerusalem, The Edmond J. Safra Campus - Givat Ram, Jerusalem, Israel.ORCID 0000-0003-1100-785X
Dina Schneidman-DuhovnyThe Rachel and Selim Benin School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0003-0480-0438
Raisa Shtuhin-RahavDepartment of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, The Edmond J. Safra Campus - Givat Ram, Jerusalem, Israel.ORCID 0000-0002-3512-2062
Naomi Melamed-BookBioimaging Unit, Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0001-9528-5026
Efrat Zlotkin-RivkinDepartment of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, The Edmond J. Safra Campus - Givat Ram, Jerusalem, Israel.ORCID 0000-0002-1396-3573
Alexander RouvinskiDepartment of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University-Hadassah Medical School, of Jerusalem, Jerusalem, Israel.ORCID 0000-0002-9917-7564
Ilan RosenshineDepartment of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University-Hadassah Medical School, of Jerusalem, Jerusalem, Israel.ORCID 0000-0001-7396-3586
Benjamin AroetiDepartment of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, The Edmond J. Safra Campus - Givat Ram, Jerusalem, Israel.ORCID 0000-0003-2023-7913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteropathogenic

Indexed as

Cell MembraneEnteropathogenic Escherichia colirab GTP-Binding ProteinsEscherichia coli InfectionsEscherichia coli ProteinsExocytosisHost-Pathogen InteractionsHumansLysosomesMechanistic Target of Rapamycin Complex 1PhosphatidylinositolsProtein BindingProto-Oncogene Proteins c-aktSignal TransductionEscherichia coli ProteinsEspH protein, E coliMechanistic Target of Rapamycin Complex 1PhosphatidylinositolsProto-Oncogene Proteins c-aktRAB8A protein, humanrab GTP-Binding Proteinsbacterial invasionEnteropathogenic e. coliEspHhost-pathogen interactionslysosomal exocytosisphosphoinositide binding domain (PBD) PI3K/Akt/mTORC1 signalingphosphoinositides (PIs)Rab GTPasesRho GTPasestype III secreted effectors

Identifiers

PMID39312647
PMCPMC11421376

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.