Evidence map›Paper›PMID 39313546›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

Sclerothrapy of giant lymphatic malformation in neonates.

Fan Hu, Fan Ma, Xiaoliang Liu, Jiayun Yu

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Thigh lymphocutaneous fistula in a child.Journal of vascular surgery. Venous and lymphatic disorders · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fan HuDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Fan MaDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Xiaoliang LiuDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Jiayun YuDepartment of Radiotherapy, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China. yujiayun88@hotmail.com.ORCID 0000-0003-4569-3093

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82102897
6 · The paper itself

Abstract

objectiveTo analyze the sclerotherapy of giant (≥8 mm) lymphatic malformations in neonates and discuss effective treatment.

methodsThis was a single-center retrospective study. Twelve patients received bleomycin (BLM) (six patients) or BLM combined with polidocanol (POL) (eight patients). The safety and effects of BLM and BLM + POL were analyzed using a t-test for categorical data and likelihood ratios or Fisher's exact test for continuous data. Factors resulting in an increased number of treatment sessions were studied.

resultsTreatment began 2-5 days after birth. The patients in the BLM group underwent more treatment sessions. Gestational age, lesion size and type, total response, and complications showed no significant differences between groups. Larger and mixed-ype lesions required more treatment sessions.

conclusionsBoth BLM group and BLM + POL group appear relatively safe and effective in neonates with giant lymphatic malformations. The combination of the two agents reduced the number of procedures and general anesthesia required.

Indexed as

BleomycinLymphatic AbnormalitiesPolyethylene GlycolsSclerosing SolutionsSclerotherapyFemaleHumansInfant, NewbornMalePolidocanolRetrospective StudiesTreatment OutcomeBleomycinPolidocanolPolyethylene GlycolsSclerosing Solutions

Identifiers

PMID39313546
PMCPMC11825356

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.