Evidence map›Paper›PMID 39314853›Full record

ArticleDrug and alcohol dependence reports2024

How substance use preferences and practices relate to fentanyl exposure among people who use drugs in Rhode Island, USA.

Leah C Shaw, Katie B Biello, Jane A Buxton, Jacqueline E Goldman, Scott E Hadland, Susan G Sherman, Yu Li, Alexandria Macmadu, Brandon D L Marshall

Abstract read
In one paragraph

Article in Drug and alcohol dependence reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leah C ShawDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Katie B BielloDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Jane A BuxtonBC Centre for Disease Control, Vancouver, BC, Canada.
Jacqueline E GoldmanDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Scott E HadlandDivision of Adolescent and Young Adult Medicine, Massachusetts General Hospital for Children, and the Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
Susan G ShermanDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Yu LiDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Alexandria MacmaduDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Brandon D L MarshallDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.

Funding

The Cascade of Care for Medicaid-Enrolled Youth with Opioid Use DisorderR01DA057566 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Scott Evan Hadland, Arthur R Williams · 2022 to 2026
$2.9M
Collaborative Care Office-Based Opioid Treatment for Adolescents and Young AdultsK23DA045085 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI HADLAND, SCOTT EVAN · 2018 to 2022
$1.1M
NIDA NIH HHS K23 DA045085NIDA NIH HHS R01 DA057566
6 · The paper itself

Abstract

Background: Over 107,000 people died in the United States (U.S.) from drug overdose in 2022, with over one million overdose deaths since 1999. The U.S. drug market is characterized by a highly toxic, unregulated, and rapidly changing supply. Understanding the extent of exposure to fentanyl among people who use drugs (PWUD) will guide public health interventions aimed to decrease overdose. Methods: We utilized baseline data from the Rhode Island Prescription and Illicit Drug Study, a randomized controlled trial of harm reduction-oriented interventions for PWUD in Rhode Island from 2020 to 2023. We evaluated sociodemographic and drug use-related covariates and examined fentanyl presence in urine drug testing (UDT). We built a classification and regression tree (CART) model to identify subpopulations with the highest likelihood of fentanyl presence in UDT. Results: Among 446 participants, those with fentanyl present in UDT tended to be younger, non-Hispanic white, and had recently injected drugs ( Conclusions: Univariate analyses and CART modeling showed substantial variation in the presence of fentanyl in UDT among PWUD. Harm reduction services for people actively injecting drugs and drug checking programs based on capacity-building, empowerment, and targeted towards those not yet engaged in services are urgently needed to support PWUD in navigating the current volatile drug supply.

Indexed as

FentanylHarm reductionOverdosePeople who use drugsSubstance use

Identifiers

PMID39314853
PMCPMC11418001

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.