Evidence map›Paper›PMID 39315019›Full record

ReviewRSC advances2024

Metal-organic frameworks in drug delivery: engineering versatile platforms for therapeutic applications.

Doaa S R Khafaga, Manar T El-Morsy, Habiba Faried, Ayah H Diab, Shaimaa Shehab, Ahmed M Saleh, Gomaa A M Ali

Abstract readReview
In one paragraph

Review in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Molecular sensing using metal-organic frameworks.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
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  11. [Research progress on immune microenvironment imbalance and targeted interventions in osteoarthritis comorbid with diabetes mellitus].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Doaa S R KhafagaHealth Sector, Faculty of Science, Galala University New Galala City 43511 Suez Egypt.ORCID https://orcid.org/0000-0002-0576-0100
Manar T El-MorsyBionanotechnology Department, Faculty of Nanotechnology, Cairo University Giza 12613 Egypt.ORCID https://orcid.org/0009-0008-5091-3306
Habiba FariedBiotechnology Department, Faculty of Science, Cairo University Giza 12613 Egypt.ORCID https://orcid.org/0009-0002-6717-8666
Ayah H DiabBiotechnology Department, Faculty of Science, Cairo University Giza 12613 Egypt.ORCID https://orcid.org/0009-0009-4792-0975
Shaimaa ShehabBiotechnology Department, Faculty of Science, Cairo University Giza 12613 Egypt.ORCID https://orcid.org/0009-0004-9767-5641
Ahmed M SalehBionanotechnology Department, Faculty of Nanotechnology, Cairo University Giza 12613 Egypt.ORCID https://orcid.org/0009-0000-8542-4053
Gomaa A M AliCollege of Marine Science and Aquatic Biology, University of Khorfakkan 18119 Sharjah United Arab Emirates gomaa.ali@ukf.ac.ae.ORCID https://orcid.org/0000-0002-7152-531X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, metal-organic frameworks (MOFs) have attracted much attention as versatile materials for drug delivery and personalized medicine. MOFs are porous structures made up of metal ions coupled with organic ligands. This review highlights the synthesis techniques used to design MOFs with specific features such as surface area and pore size, and the drug encapsulation within MOFs not only improves their stability and solubility but also allows for controlled release kinetics, which improves therapeutic efficacy and minimizes adverse effects. Furthermore, it discusses the challenges and potential advantages of MOF-based drug delivery, such as MOF stability, biocompatibility, and scale-up production. With further advancements in MOF synthesis, functionalization techniques, and understanding of their interactions using biological systems, MOFs can have significant promise for expanding the area of personalized medicine and improving patient outcomes.

Identifiers

PMID39315019
PMCPMC11418013

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.