Evidence map›Paper›PMID 39317678›Full record

ArticleAlcohol, clinical & experimental research2024

Pain and unhealthy alcohol use among people living with HIV: A prospective cohort study.

Tibor P Palfai, Michael R Winter, Kara M Magane, Timothy C Heeren, Lauren B Bernier, Grace E Murray, Richard Saitz, Theresa W Kim, Michael D Stein

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tibor P PalfaiDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-3334-5203
Michael R WinterDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
Kara M MaganeDepartment of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts, USA.
Timothy C HeerenDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
Lauren B BernierDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.
Grace E MurrayDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.
Richard SaitzDepartment of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts, USA.
Theresa W KimClinical Addiction Research and Education (CARE) Unit, Section of General Internal Medicine, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-6043-0721
Michael D SteinGrayken Center for Addiction, Boston Medical Center, Boston, Massachusetts, USA.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
Integrated telehealth intervention to reduce chronic pain and unhealthy drinking among people living with HIVP01AA029546 · NIAAA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SAITZ, RICHARD · 2021 to 2025
$7.4M
URBAN ARCH (5/5) Boston Cohort - Alcohol and HIV-associated comorbidity and complications: Frailty, Functional impairment, Falls, and Fractures (the 4F study)U01AA020784 · NIAAA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HEEREN, TIMOTHY C., KIM, THERESA W · 2011 to 2021
$6.4M
NIAAA NIH HHS P01 AA029546NIAAA NIH HHS U01 AA020784NIAID NIH HHS P30 AI042853NIH HHS P01AA029546NIH HHS U01AA020784
6 · The paper itself

Abstract

backgroundUnhealthy alcohol use is prevalent among people living with HIV/AIDS (PLWH) and contributes to impaired functioning, diminished quality of life, and poorer HIV outcomes. Common cooccurring conditions such as chronic pain may be associated with negative outcomes both directly and through its influence on unhealthy drinking itself. However, there is relatively little known about how pain influences unhealthy drinking among PLWH over time. The current study examined whether pain was associated with indices of unhealthy alcohol use, namely heavy drinking and alcohol use disorder (AUD) assessed 12 months later.

methodsThe study sample (n = 207) was from the Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort, a prospective cohort of PLWH with a history of illicit substance or unhealthy alcohol use. We conducted logistic regression analyses to examine the associations between pain and both heavy drinking and AUD status (DSM-5 criteria) (yes/no) over time. In secondary analyses, we examined whether pain was associated with greater AUD severity and whether pain interference was associated with heavy drinking and AUD outcomes.

resultsWe found that pain at baseline was associated with greater odds of AUD [aOR = 2.29 (95% CI: 1.13, 4.64), p = 0.02] but not heavy drinking [aOR = 0.91 (95% CI: 0.44, 1.88), p = 0.79] at 12 months. Pain was also associated with more severe AUD. Analyses of pain interference showed similar results.

conclusionsPain is prospectively associated with higher odds of AUD among PLWH with a substance/unhealthy alcohol use history. Providers should routinely address pain among PLWH to improve AUD outcomes.

Indexed as

alcoholalcohol use disorderheavy drinkingHIVpain

Identifiers

PMID39317678
PMCPMC11884506

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.