Evidence map›Paper›PMID 39318328›Full record

Trial reportClinical rehabilitation2024

Providing Emotional Support During the Process of Multiple Sclerosis Diagnosis (PrEliMS): A Feasibility Randomised Controlled Trial.

Roshan das Nair, Jacqueline R Mhizha-Murira, Gogem Topcu, Tierney Tindall, Clare Bale, Nima Moghaddam, Grit Scheffler-Ansari, Avril Drummond, Deborah Fitzsimmons, Nikos Evangelou

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Roshan das NairSchool of Medicine, University of Nottingham, Nottingham, UK.
Jacqueline R Mhizha-MuriraSchool of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0002-1976-0195
Gogem TopcuSchool of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0002-7400-5686
Tierney TindallSchool of Medicine, University of Nottingham, Nottingham, UK.
Clare BaleMultiple Sclerosis Patient and Public Involvement Group, Nottingham, UK.
Nima MoghaddamSchool of Medicine, University of Nottingham, Nottingham, UK.
Grit Scheffler-AnsariSchool of Medicine, University of Nottingham, Nottingham, UK.
Avril DrummondSchool of Health Sciences, University of Nottingham, Nottingham, UK.
Deborah FitzsimmonsSwansea Centre for Health Economics, Swansea University, Swansea, UK.ORCID 0000-0002-7286-8410
Nikos EvangelouSchool of Medicine, University of Nottingham, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the feasibility and acceptability of an emotional support programme for newly diagnosed people with multiple sclerosis.

designThree-arm, mixed methods, randomised controlled trial comparing usual care, versus usual care plus nurse-specialist support, versus usual care plus nurse-specialist support plus peer support.

participantsCommunity-dwelling adults within two years of diagnosis

interventionsPrEliMS involves information provision, emotional support, and strategies and techniques based on psychoeducation, Acceptance and Commitment Therapy principles, supportive listening. One version of the intervention was provided by nurse-specialists alone and the other was provided by nurse-specialists plus peer support. MAIN MEASURES: The main outcome of interest was the feasibility of proceeding to a definitive trial, exploring recruitment rate, acceptability, completion of outcome measures (perceived stress, mood, self-efficacy, psychological impact, and service use), and signal of efficacy.

resultsOf 40 participants randomised (mean age 36.2 years (SD = 14.8); 54% women; 85% with relapsing-remitting MS), 36 and 38 returned 3- and 6-month questionnaires, respectively. Participant interviews suggested the trial was largely feasible, and the intervention acceptable, with some amendments to trial procedures and intervention delivery noted. There were, however, no statistically significant differences between groups at followup for any measures, and effect-size estimates were small.

conclusionA definitive trial combining nurse-specialist and peer support adjustment to diagnosis intervention is warranted, but more work exploring the delivery and fidelity of the intervention is needed before this is pursued.

Indexed as

Feasibility StudiesMultiple SclerosisSocial SupportAdultFemaleHumansMaleMiddle Ageddiagnosisemotional supportMultiple sclerosispeer supportpsychological adjustment

Identifiers

PMID39318328
PMCPMC11528975

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.