Evidence map›Paper›PMID 39318449›Full record

ArticleEuropean heart journal. Imaging methods and practice2024

A simplified approach to discriminate between healthy subjects and patients with heart failure using cardiac magnetic resonance myocardial deformation imaging.

Undine Ella Witt, Maximilian Leo Müller, Rebecca Elisabeth Beyer, Johannes Wieditz, Susanna Salem, Djawid Hashemi, Wensu Chen, Mina Cvetkovic, Anna Clara Nolden, Patrick Doeblin and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in European heart journal. Imaging methods and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07185100 (A Prospective, Cross-sectional, Nationwide Community-based Observational Study to Determine the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07185100 recruitingnot on this mapstarted 2025, after this paper: background citation

A Prospective, Cross-sectional, Nationwide Community-based Observational Study to Determine the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR

TypeobservationalSponsorGerman Heart InstituteRan2025 to 2036Enrolled600ConditionsHeart Failure With Preserved Ejection Fraction (HFPEF), Renal Dysfunction, Stage B Heart Failure
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Design and rationale of the WE-CARE-HF-CMR trial: Cardiorenal care on wheels for asymptomatic heart failure patients (NCT07185100).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Exercise cardiovascular magnetic resonance myocardial dynamic index: A non-invasive imaging marker associated with cardiac dyspnea.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Undine Ella WittDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.
Maximilian Leo MüllerDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.ORCID https://orcid.org/0000-0002-6281-9754
Rebecca Elisabeth BeyerDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.ORCID https://orcid.org/0009-0007-9373-0756
Johannes WieditzDepartment of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.
Susanna SalemDepartment of Medical Statistics, University Medical Center Göttingen, Göttingen, Germany.
Djawid HashemiDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.
Wensu ChenDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-8956-3672
Mina CvetkovicDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.
Anna Clara NoldenDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.
Patrick DoeblinDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.
Moritz BlumCorporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Gisela ThiedeDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.
Alexander HuppertzUniversity Outpatient Clinic, Sports Medicine and Sports Orthopaedics, University of Potsdam, Potsdam, Germany.
Henning SteenDepartment of Cardiology, Angiology and Pneumology, Heidelberg University, Heidelberg, Germany.
Bjoern Andrew RemppisDepartment of Cardiology, Cardiovascular Center Bad Bevensen, Bad Bevensen, Germany.
Volkmar FalkCorporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0002-7911-8620
Tim FriedeDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-5347-7441
Sebastian KelleDepartment of Cardiology, Deutsches Herzzentrum der Charité, Angiology and Intensive Care Medicine, Augustenburger Platz 1, Berlin 13353, Germany.ORCID https://orcid.org/0000-0001-8105-6599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Left ventricular global longitudinal strain (LV-GLS) shows promise as a marker to detect early heart failure (HF). This study sought to (i) establish cardiac magnetic resonance imaging (CMR)-derived LV-GLS cut-offs to differentiate healthy from HF for both acquisition-based and post-processing techniques, (ii) assess agreement, and (iii) provide a method to convert LV-GLS between both techniques. Methods and results: A secondary analysis of a prospective study enrolling healthy subjects ( Conclusion: LV-GLS distinguishes healthy from HF with high accuracy. Each measurement technique requires distinct cut-offs, but rescaling factors facilitate conversion. An FT-based LV-GLS ≥ -15% simplifies HF detection in clinical routine.

Indexed as

cardiac magnetic resonance imagingcut-offdeformation imagingearly identification of heart failureglobal longitudinal strain

Identifiers

PMID39318449
PMCPMC11421468

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.