Evidence mapPaperPMID 39318593Full record

ArticleFrontiers in medicine2024

Closed-loop oxygen usage during invasive mechanical ventilation of pediatric patients (CLOUDIMPP): a randomized controlled cross-over study.

Gulhan Atakul, Gokhan Ceylan, Ozlem Sandal, Ekin Soydan, Pinar Hepduman, Mustafa Colak, Jan M Zimmermann, Dominik Novotni, Utku Karaarslan, Sevgi Topal and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05714527 (Closed-Loop O2 Use During Invasive Mechanical Ventilation Of Pediatric Patients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05714527 nacompletednot on this map

Closed-Loop O2 Use During Invasive Mechanical Ventilation Of Pediatric Patients (CLOUDIMPP)- a Randomized Cross-over Study

TypeinterventionalSponsorDr. Behcet Uz Children's HospitalRan2023 to 2024Enrolled30ConditionsRespiratory FailureArmsClose-loop FiO2 controller, Conventional
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gulhan AtakulDepartment of Paediatric Intensive Care Unit, Dr Behcet Uz Children's Disease and Surgery Training and Research Hospital, Health Sciences University, Izmir, Türkiye.
Gokhan CeylanDepartment of Paediatric Intensive Care Unit, Dr Behcet Uz Children's Disease and Surgery Training and Research Hospital, Health Sciences University, Izmir, Türkiye.
Ozlem SandalDepartment of Paediatric Intensive Care Unit, Dr Behcet Uz Children's Disease and Surgery Training and Research Hospital, Health Sciences University, Izmir, Türkiye.
Ekin SoydanDepartment of Paediatric Intensive Care Unit, Aydin Obstetrics and Children Hospital, Health Sciences University, Aydin, Türkiye.
Pinar HepdumanDepartment of Paediatric Intensive Care Unit, Erzurum Territorial Training and Research Hospital, Health Sciences University, Erzurum, Türkiye.
Mustafa ColakDepartment of Paediatric Intensive Care Unit, Cam Sakura Training and Research Hospital, Health Sciences University, Istanbul, Türkiye.
Jan M ZimmermannDepartment of Medical Research, Hamilton Medical AG, Chur, Switzerland.
Dominik NovotniDepartment of Medical Research, Hamilton Medical AG, Chur, Switzerland.
Utku KaraarslanDepartment of Paediatric Intensive Care Unit, Dr Behcet Uz Children's Disease and Surgery Training and Research Hospital, Health Sciences University, Izmir, Türkiye.
Sevgi TopalDepartment of Paediatric Intensive Care Unit, Erzurum Territorial Training and Research Hospital, Health Sciences University, Erzurum, Türkiye.
Hasan AǧinDepartment of Paediatric Intensive Care Unit, Dr Behcet Uz Children's Disease and Surgery Training and Research Hospital, Health Sciences University, Izmir, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study is the evaluation of a closed-loop oxygen control system in pediatric patients undergoing invasive mechanical ventilation (IMV). Methods: Cross-over, multicenter, randomized, single-blind clinical trial. Patients between the ages of 1 month and 18 years who were undergoing IMV therapy for acute hypoxemic respiratory failure (AHRF) were assigned at random to either begin with a 2-hour period of closed-loop oxygen control or manual oxygen titrations. By using closed-loop oxygen control, the patients' SpO Findings: The median age of included 33 patients was 17 (13-55.5) months. In contrast to manual oxygen titrations, patients spent a greater proportion of time within a predefined optimal SpO Conclusion: Closed-loop oxygen control enhances oxygen therapy in pediatric patients undergoing IMV for AHRF, potentially leading to more efficient utilization of oxygen. This technology also decreases the necessity for manual adjustments, which could reduce the workloads of healthcare providers. Clinical Trial Registration: This research has been submitted to ClinicalTrials.gov (NCT05714527).

Indexed as

automationclosed-loophypoxemiaintensive careinvasive mechanical ventilationoxygen controlleroxygen therapypediatrics

Identifiers

PMID39318593
PMCPMC11420134

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.