Evidence map›Paper›PMID 39318717›Full record

Trial reportF1000Research2024

The effects of multifactorial pharmacist-led intervention protocol on medication optimisation and adherence among patients with type 2 diabetes: A randomised control trial.

Marwan El-Deyarbi, Luai Ahmed, Jeffrey King, Syed Abubackar, Ahmed Al Juboori, Nirmin A Mansour, Salahdein Aburuz

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in F1000Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marwan El-DeyarbiDepartment of Pharmacy, Oud Al-Touba Diagnostic and Screening Clinic, Ambulatory Health Services, Abu Dhabi Health Services Co. SEHA, Al Ain, Abu Dhabi, 00971, United Arab Emirates.ORCID https://orcid.org/0000-0001-6331-4259
Luai AhmedInstitute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, Abu Dhabi, 00971, United Arab Emirates.ORCID https://orcid.org/0000-0001-5292-8212
Jeffrey KingDepartment of Veterans Affairs, Department of Geriatrics and Extended Care, Greater Los Angeles Veterans Research and Education Foundation, Los Angeles, California, USA.
Syed AbubackarDepartment of Pharmacy, Oud Al-Touba Diagnostic and Screening Clinic, Ambulatory Health Services, Abu Dhabi Health Services Co. SEHA, Al Ain, Abu Dhabi, 00971, United Arab Emirates.
Ahmed Al JubooriDivision of Endocrinology, Oud Al-Touba Diagnostic and Screening Clinic, Ambulatory Health Services, Abu Dhabi Health Services Co. SEHA, Al Ain, Abu Dhabi, 00971, United Arab Emirates.
Nirmin A MansourDivision of Endocrinology, Oud Al-Touba Diagnostic and Screening Clinic, Ambulatory Health Services, Abu Dhabi Health Services Co. SEHA, Al Ain, Abu Dhabi, 00971, United Arab Emirates.
Salahdein AburuzDepartment of Pharmacology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, Abu Dhabi, 00971, United Arab Emirates.ORCID https://orcid.org/0000-0002-2478-3914

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patient-related factors and limited medication adherence in patients with chronic diseases, are associated with poor clinical outcomes, long-term complications, and increased overall disease costs. Many methods have been tested with mixed results, and innovative approaches are needed to encourage patients to adhere to their prescribed drug regimens. Methods: This randomised controlled trial examined a new multifactorial pharmacist-led intervention protocol (MPIP), including a medication therapy management (MTM) program with face-to-face counselling, patient-specific medication booklets, and a mobile application, from July 2021 to September 2022 in the Oud Al Touba diagnostic and screening ambulatory centre in 192 patients with type 2 diabetes in the United Arab Emirates. Medication adherence was assessed using the fixed medication possession ratio of medication refills and the medication adherence questionnaire. Results: At 12 months follow-up, participants in the MPIP showed significant improvement in overall medication adherence with total (composite) medication possession ratio (MPRt) of mean (±SD) 0.95 (±0.09) compared to 0.92 (± 0.09) in the control group with mean difference of 0.03 (95%, CI 0.01-0.06), P =0.02. In addition, improvement trend was evident in the MPIP group for all medication regimens with P value <0.01. Comparable results were noticeable in adherence questionnaire scores at the end of the study, with 66 participants in the intervention group scored zero on the questionnaire, suggesting high adherence to medication compared to the control group (48 participants only). The MTM program performed 41 clinical interventions on drug-related problems, compared to six interventions in the control group, and the use of mobile application and medication booklet have increased to 45.7% compared to 21.4% before study exit. Conclusions: The pharmacy intervention protocol effectively improved medication adherence and optimised medication regimens in diabetic patients with chronic medication regimens in an ambulatory healthcare centre.

Indexed as

Diabetes Mellitus, Type 2Medication AdherencePharmacistsAdultAgedFemaleHumansHypoglycemic AgentsMaleMedication Therapy ManagementMiddle AgedUnited Arab EmiratesHypoglycemic AgentsDiabetesfixed medication possession ratiomedication adherencemedication therapy managementmobile applicationpharmacist-led

Identifiers

PMID39318717
PMCPMC11421608

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.