Evidence map›Paper›PMID 39320341›Full record

ReviewClinical cancer research : an official journal of the American Association for Cancer Research2024

Update on Surveillance for Wilms Tumor and Hepatoblastoma in Beckwith-Wiedemann Syndrome and Other Predisposition Syndromes.

Jennifer M Kalish, Kerri D Becktell, Gaëlle Bougeard, Garrett M Brodeur, Lisa R Diller, Andrea S Doria, Jordan R Hansford, Steven D Klein, Wendy K Kohlmann, Christian P Kratz and 10 more

Abstract readReview
In one paragraph

Review in Clinical cancer research : an official journal of the American Association for Cancer Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
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  6. Review
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  11. Clinical practice guidelines for the management of differences of sex development in Japan.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Pediatric Cancer Predisposition and Surveillance Update: Summary Perspective and Future Directions.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Review
  18. Hepatoblastoma.Nature reviews. Disease primers · 2025
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jennifer M KalishDivision of Human Genetics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0003-1500-9713
Kerri D BecktellDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0002-1935-5157
Gaëlle BougeardDepartment of Genetics, University Rouen Normandie, Inserm U1245, Normandie University, CHU Rouen, Rouen, France.ORCID 0000-0002-1475-0254
Garrett M BrodeurDepartment of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-6721-122X
Lisa R DillerDepartment of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.ORCID 0000-0002-4073-5509
Andrea S DoriaDepartment of Diagnostic and Interventional Radiology, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0003-3202-0447
Jordan R HansfordMichael Rice Centre for Hematology and Oncology, Women's and Children's Hospital, South Australia Health and Medical Research Institute, South Australia ImmunoGENomics Cancer Institute, University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0001-7733-383X
Steven D KleinDivision of Human Genetics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0001-8634-0388
Wendy K KohlmannVA Medical Center, National TeleOncology, Clinical Cancer Genetics Service, Durham VA, University of Utah Huntsman Cancer Institute, Salt Lake City, Utah.ORCID 0000-0002-9134-9640
Christian P KratzPediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.ORCID 0000-0003-4120-5873
Suzanne P MacFarlandDepartment of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-5894-6403
Kristian W PajtlerHopp Children's Cancer Center (KiTZ), Heidelberg, Germany.ORCID 0000-0002-3562-6121
Surya P RednamDivision of Hematology and Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.ORCID 0000-0001-8333-0758
Jaclyn SchiendaDepartment of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.ORCID 0000-0003-2543-8378
Lisa J StatesDepartment of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0003-0260-3975
Anita VillaniDivision of Paediatric Haematology and Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0003-3283-2197
Rosanna WeksbergDivision of Clinical and Metabolic Genetics, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-6501-4150
Kristin ZelleyCenter for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0003-0970-1850
Gail E TomlinsonDivision of Hematology-Oncology, Department of Pediatrics, Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas.ORCID 0000-0003-2579-1833
Jack J BrzezinskiDivision of Clinical and Metabolic Genetics, Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-9475-0077

Funding

The Mechanism of Tumor Formation in Beckwith-Wiedemann SyndromeK08CA193915 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI KALISH, JENNIFER MELISSA · 2015 to 2019
$703k
Alex's Lemonade Stand Foundation for Childhood Cancer (ALSF)Damon Runyon Cancer Research Foundation (DRCRF) 105-19Deutsche Kinderkrebsstiftung (German Childhood Cancer Foundation) DKS 2024.03Hospital Research Foundation (HRF)Jamie McClurg FoundationLorenzo "Turtle" Sartini Jr Endowed Chair in Beckwith-Wiedemann Syndrome Research and the Victoria Fertitta FundNCI NIH HHS K08 CA193915Rally Foundation for Childhood Cancer Research Career Development AwardSt Baldricks Foundation for Childhood Cancer Research
6 · The paper itself

Abstract

Wilms tumors are commonly associated with predisposition syndromes, many but not all of which include overgrowth. Several of these syndromes also include a risk of other embryonal malignancies-particularly hepatoblastoma. Guidelines for surveillance in this population were published in 2017, and recently, members of the American Association for Cancer Research Pediatric Cancer Working Group met to update those guidelines with a review of more recently published evidence and risk estimates. This perspective serves to update pediatric oncologists, geneticists, radiologists, counselors, and other health care professionals on revised diagnostic criteria; review previously published surveillance guidelines; and harmonize updated surveillance recommendations in the North American and Australian contexts for patients with overgrowth syndromes and other syndromes associated with Wilms tumor predisposition.

Indexed as

Beckwith-Wiedemann SyndromeHepatoblastomaWilms TumorAustraliaGenetic Predisposition to DiseaseHumansKidney NeoplasmsLiver NeoplasmsPractice Guidelines as Topic

Identifiers

PMID39320341
PMCPMC11611621

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.