Evidence map›Paper›PMID 39321554›Full record

Trial reportRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)2025

Effect of home-based transcranial direct current stimulation combined with nutritional counseling therapy on binge eating disorder symptoms: a randomized pilot trial.

Jessica Lorenzzi Elkfury, Luciana C Antunes, Betina Franceschini Tocchetto, Lizia Nardi Menegassi, Paulo Sanches, Danton Pereira, Liciane Fernandes Medeiros, Tiago M Cardinal, Iraci L S Torres, Felipe Fregni and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jessica Lorenzzi ElkfuryPrograma de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Laboratório de Dor e Neuromodulação, UFRGS, Porto Alegre, RS, Brazil.
Luciana C AntunesLaboratório de Dor e Neuromodulação, UFRGS, Porto Alegre, RS, Brazil. Departamento de Nutrição, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Betina Franceschini TocchettoPrograma de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Laboratório de Dor e Neuromodulação, UFRGS, Porto Alegre, RS, Brazil.
Lizia Nardi MenegassiLaboratório de Dor e Neuromodulação, UFRGS, Porto Alegre, RS, Brazil.
Paulo SanchesLaboratório de Engenharia Biomédica, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Danton PereiraLaboratório de Engenharia Biomédica, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
Liciane Fernandes MedeirosPrograma de Pós-Graduação em Saúde e Desenvolvimento Humano, Universidade La Salle, Canoas, RS, Brazil. Programa de Pós-Graduação em Ciências Biológicas: Farmacologia e Terapêutica, UFRGS, Porto Alegre, RS, Brazil. Núcleo de Pesquisa em Farmacologia da Dor e Neuromodulação, HCPA, RS, Brazil.
Tiago M CardinalLaboratório de Dor e Neuromodulação, UFRGS, Porto Alegre, RS, Brazil.
Iraci L S TorresPrograma de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Núcleo de Pesquisa em Farmacologia da Dor e Neuromodulação, HCPA, RS, Brazil.
Felipe FregniSpaulding Neuromodulation Center, Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Charleston, SC, USA.
Wolnei CaumoPrograma de Pós-Graduação em Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Laboratório de Dor e Neuromodulação, UFRGS, Porto Alegre, RS, Brazil. Departamento de Cirurgia, Faculdade de Medicina, UFRGS, Porto Alegre, RS, Brazil.

Funding

Fundo de Incentivo à Pesquisa e Eventos/Hospital de Clínicas de Porto AlegrePrograma de Pós-Graduação em Ciências da Saúde/Universidade Federal do Rio Grande do Sul
6 · The paper itself

Abstract

objectiveTo examine the effect of nutritional counseling therapy (NCT) combined with transcranial direct current stimulation (tDCS) on binge eating disorder (BED) symptoms.

methodsForty women with BED were randomly allocated (2:2:2 ratio) to one of the following groups: active tDCS (a-tDCS), NCT, sham tDCS (s-tDCS) with NCT, and a-tDCS with NCT. Home-based tDCS was applied to the dorsolateral prefrontal cortex for 28 sessions.

resultsA mixed analysis of variance (ANOVA) showed no main effect between groups nor a time × group interaction. However, a significant main effect was found for time on the primary outcome Binge Eating Scale (BES) (p = 0.001; eta2p = 0.325), which tended to decrease during treatment and follow-up. A significant main effect was found for the secondary outcome short-interval intracortical inhibition (SICI) (p = 0.02; eta2p = 0.112), a measure of inhibitory function, which increased from baseline to the final period in the a-tDCS group, without significant differences between groups.

conclusionCombined NCT and tDCS did not have a synergistic effect on BED symptoms. Nevertheless, the data from this pilot study should help plan future larger-scale studies investigating the effects of tDCS and behavioral interventions in the promising area of BED treatment.

Indexed as

Binge-Eating DisorderCounselingNutrition TherapyTranscranial Direct Current StimulationAdultAnalysis of VarianceCombined Modality TherapyFemaleHumansMiddle AgedPilot ProjectsTime FactorsTreatment OutcomeYoung AdultBinge eating disordercortical excitabilitynutritional therapytranscranial direct current stimulation

Identifiers

PMID39321554
PMCPMC12812372

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.