Evidence map›Paper›PMID 39322752›Full record

ReviewNature methods2024

Controlling the sound of light: photoswitching optoacoustic imaging.

Andre C Stiel, Vasilis Ntziachristos

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Optical and Optoacoustic Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  9. Review
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andre C StielInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany. andre.stiel@helmholtz-muenchen.de.ORCID http://orcid.org/0000-0001-8675-6797
Vasilis NtziachristosInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany. v.ntziachristos@tum.de.ORCID http://orcid.org/0000-0002-9988-0233

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) STI-656/5-1Deutsche Forschungsgemeinschaft (German Research Foundation) STI-656/6-1EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 101002646 ('Switch2See')
6 · The paper itself

Abstract

Optoacoustic (photoacoustic) imaging advances allow high-resolution optical imaging much deeper than optical microscopy. However, while label-free optoacoustics have already entered clinical application, biological imaging is in need of ubiquitous optoacoustic labels for use in ways that are similar to how fluorescent proteins propelled optical microscopy. We review photoswitching advances that shine a new light or, in analogy, 'bring a new sound' to biological optoacoustic imaging. Based on engineered labels and novel devices, switching uses light or other energy forms and enables signal modulation and synchronous detection for maximizing contrast and detection sensitivity over other optoacoustic labels. Herein, we explain contrast enhancement in the spectral versus temporal domains and review labels and key concepts of switching and their properties to modulate optoacoustic signals. We further outline systems and applications and discuss how switching can enable optoacoustic imaging of cellular or molecular contrast at depths and resolutions beyond those of other optical methods.

Indexed as

Photoacoustic TechniquesAnimalsHumansLight

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.