ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2024
Trajectories of daily antipsychotic use and weight gain in people hospitalized for the first episode of psychosis.
Article in European psychiatry : the journal of the Association of European Psychiatrists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundWe need to better understand the risk factors and predictors of medication-related weight gain to improve metabolic health of individuals with schizophrenia. This study explores how trajectories of antipsychotic medication (AP) use impact body weight early in the course of schizophrenia.
methodsWe recruited 92 participants with first-episode psychosis (FEP,
resultsMost people started treatment with risperidone (
conclusionsEarly in the course of illness, during inpatient treatment, baseline BMI is the strongest and earliest predictor of weight gain on APs and is a better predictor than type of medication, polypharmacy, or medication switches. Baseline BMI predicted weight change over a period of weeks, when other traditional predictors demonstrated a much smaller effect.
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