Evidence map›Paper›PMID 39324365›Full record

Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

Number of conditioning trials, but not stimulus intensity, influences operant conditioning of brain responses after total knee arthroplasty.

Kazandra M Rodriguez, Chandramouli Krishnan, Riann M Palmieri-Smith

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kazandra M RodriguezSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID http://orcid.org/0000-0002-4947-8510
Chandramouli KrishnanSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID http://orcid.org/0000-0002-7278-7389
Riann M Palmieri-SmithSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID http://orcid.org/0000-0001-6790-3691

Funding

University of Michigan Rackham Graduate Student Research Grant
6 · The paper itself

Abstract

purposeThe primary purpose of this randomized, cross-sectional study was to determine whether operant conditioning of motor evoked torque (MEP

methodsThirty participants were block-randomized into one of three groups based on the participant's active motor threshold (100%, 120%, and 140%) to evaluate the effect of stimulus intensity. Participants received three blocks of conditioning trials (COND), where they trained to increase their MEP

resultsTKA participants were able to successfully increase their MEP

conclusionOperant conditioning is a feasible approach for improving quadriceps corticospinal excitability following TKA. While any of the three stimulus intensities evaluated in this study may be used in future operant conditioning interventions, using a low or moderate stimulus intensity and 150 training trials are recommended to improve treatment efficiency and patient adherence. LEVEL OF EVIDENCE: Level II.

Indexed as

Arthroplasty, Replacement, KneeConditioning, OperantEvoked Potentials, MotorQuadriceps MuscleAdaptation, PhysiologicalAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPyramidal TractsTorqueTranscranial Magnetic Stimulationcortical excitabilityknee replacementmotor learningneurorehabilitationpsychomotor performance

Identifiers

PMID39324365
PMCPMC11848966

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.