Evidence map›Paper›PMID 39325002›Full record

ArticleDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society2025

Comorbidity burden and outcomes of endoscopic ultrasound-guided treatment of pancreatic fluid collections: Multicenter study with nationwide data-based validation.

Tsuyoshi Hamada, Atsuhiro Masuda, Nobuaki Michihata, Tomotaka Saito, Masahiro Tsujimae, Mamoru Takenaka, Shunsuke Omoto, Takuji Iwashita, Shinya Uemura, Shogo Ota and 18 more

Abstract readMulticenter StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Tsuyoshi HamadaDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3937-2755
Atsuhiro MasudaDivision of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan.
Nobuaki MichihataDepartment of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Tomotaka SaitoDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Masahiro TsujimaeDivision of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan.
Mamoru TakenakaDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Kindai University, Osaka, Japan.ORCID https://orcid.org/0000-0001-7308-4311
Shunsuke OmotoDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Kindai University, Osaka, Japan.
Takuji IwashitaFirst Department of Internal Medicine, Gifu University Hospital, Gifu, Japan.ORCID https://orcid.org/0000-0003-4978-1787
Shinya UemuraFirst Department of Internal Medicine, Gifu University Hospital, Gifu, Japan.
Shogo OtaDivision of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan.
Hideyuki ShiomiDivision of Hepatobiliary and Pancreatic Diseases, Department of Gastroenterology, Hyogo Medical University, Hyogo, Japan.ORCID https://orcid.org/0000-0002-7461-8538
Toshio FujisawaDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7367-0767
Sho TakahashiDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Saburo MatsubaraDepartment of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Kentaro SudaDepartment of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Hiroki MatsuiDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Akinori MarutaDepartment of Gastroenterology, Gifu Prefectural General Medical Center, Gifu, Japan.
Kensaku YoshidaDepartment of Gastroenterology, Gifu Prefectural General Medical Center, Gifu, Japan.
Keisuke IwataDepartment of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
Mitsuru OkunoDepartment of Gastroenterology, Gifu Municipal Hospital, Gifu, Japan.
Nobuhiko HayashiThird Department of Internal Medicine, University of Toyama, Toyama, Japan.
Tsuyoshi MukaiDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Ishikawa, Japan.
Kiyohide FushimiDepartment of Health Policy and Informatics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Ichiro YasudaThird Department of Internal Medicine, University of Toyama, Toyama, Japan.ORCID https://orcid.org/0000-0002-6888-0310
Hiroyuki IsayamaDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3308-9326
Hideo YasunagaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Yousuke NakaiDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7411-1385
WONDERFUL study group in Japan and collaborators

Funding

Daiichi Sankyo CompanyJapan Society for the Promotion of Science JP19K08362Japan Society for the Promotion of Science JP22H02841Takeda Science Foundationthe Ministry of Health, Labour, and Welfare, Japan 22AA2003the Ministry of Health, Labour, and Welfare, Japan 23AA2003
6 · The paper itself

Abstract

objectivesThe appropriate holistic management is mandatory for successful endoscopic ultrasound (EUS)-guided treatment of pancreatic fluid collections (PFCs). However, comorbidity status has not been fully examined in relation to clinical outcomes of this treatment.

methodsUsing a multi-institutional cohort of 406 patients receiving EUS-guided treatment of PFCs in 2010-2020, we examined the associations of Charlson Comorbidity Index (CCI) with in-hospital mortality and other clinical outcomes. Multivariable logistic regression analysis was conducted with adjustment for potential confounders. The findings were validated using a Japanese nationwide inpatient database including 4053 patients treated at 486 hospitals in 2010-2020.

resultsIn the clinical multi-institutional cohort, CCI was positively associated with the risk of in-hospital mortality (P

conclusionsHigher levels of CCI were associated with a higher risk of in-hospital mortality among patients receiving EUS-guided treatment of PFCs, suggesting the potential of CCI in stratifying the periprocedural mortality risk.

trial registrationThe research based on the clinical data from the WONDERFUL cohort was registered with UMIN-CTR (registration number UMIN000044130).

Indexed as

DrainageEndosonographyPancreatic DiseasesUltrasonography, InterventionalAgedAged, 80 and overComorbidityFemaleHospital MortalityHumansJapanMaleMiddle AgedRetrospective StudiesTreatment Outcomeacute necrotizing pancreatitiscohort studyendosonographyrisk factorstent

Identifiers

PMID39325002
PMCPMC11986896

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.