Evidence map›Paper›PMID 39327992›Full record

ArticleTechnology in cancer research & treatment

Oncogenic microRNA-1290 and

Rashida Naseem, Samiah Shahid, Wajeehah Shahid, Ghulam Abbas

Abstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rashida NaseemInstitute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.
Samiah ShahidInstitute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.ORCID 0000-0003-0122-6629
Wajeehah ShahidDepartment of Physics, The University of Lahore, Lahore, Pakistan.
Ghulam AbbasDepartment of Gastroenterology, Allama Iqbal Medical college, Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionColorectal cancer (CRC) is the world's third most frequent cancer, with a significant mortality rate due to late detection. There is a need to search for biomarkers that can detect colorectal cancer at an early stage. MicroRNAs (miRNAs) regulate several targets that function as oncogenes and/or tumor suppressor genes, so any change in microRNA expression level can predict abnormality.

objectiveThe objective of the study was to evaluate the expression of miR-1290, and METHODOLOGY: This study included 50 subjects consisting of newly diagnosed colorectal carcinoma patients (

resultsWe found that miR-1290 is upregulated, whereas

conclusionThe expression of miR-1290 and

Indexed as

Biomarkers, TumorColorectal NeoplasmsGene Expression Regulation, NeoplasticMicroRNAsAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedNeoplasm StagingROC CurveBiomarkers, TumorMicroRNAsMIRN1290 microRNA, humancarcinomacolorectal cancergene expressionmiRsuppressor of cancer cell invasion

Identifiers

PMID39327992
PMCPMC11439174

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.