Evidence map›Paper›PMID 39328571›Full record

ReviewHeliyon2024

Impact of the environmental pollution on cardiovascular diseases: From epidemiological to molecular evidence.

Manuel Scimeca, Valeria Palumbo, Erica Giacobbi, Francesca Servadei, Stefano Casciardi, Elena Cornella, Federica Cerbara, Gabriele Rotondaro, Christian Seghetti, Maria Paola Scioli and 6 more

Abstract readReview
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  9. Trends in ischemic heart disease mortality among older adults with co-existing colorectal cancer in the US (1999-2023): a 25-Year retrospective study.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Manuel ScimecaDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Valeria PalumboDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Erica GiacobbiDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Francesca ServadeiDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Stefano CasciardiDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL Research, Monte Porzio Catone, Rome, 00078, Italy.
Elena CornellaDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Federica CerbaraDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Gabriele RotondaroDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Christian SeghettiDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Maria Paola ScioliDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Manuela MontanaroDepartment of Biomedicine and Prevention, Tor Vergata University of Rome, 00133, Rome, Italy.
Francesco BarillàDepartment of Systems Medicine, Tor Vergata University, 00133, Rome, Italy.
Renata SistoDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL Research, Monte Porzio Catone, Rome, 00078, Italy.
Gerry MelinoDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Alessandro MaurielloDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.
Rita BonfiglioDepartment of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental pollution poses a significant threat to human health, particularly concerning its impact on cardiovascular diseases (CVDs). This review synthesizes epidemiological and molecular evidence to elucidate the intricate relationship between environmental pollutants and CVDs. Epidemiological studies highlight the association between exposure to air, water, and soil pollutants and increased CVD risk, including hypertension, coronary artery disease, and stroke. Furthermore, molecular investigations unravel the underlying mechanisms linking pollutant exposure to CVD pathogenesis, such as oxidative stress, inflammation, endothelial dysfunction, and autonomic imbalance. Understanding these molecular pathways is crucial for developing targeted interventions and policy strategies to mitigate the adverse effects of environmental pollution on cardiovascular health. By integrating epidemiological and molecular evidence, this review provides insights into the complex interplay between environmental factors and CVDs, emphasizing the urgent need for comprehensive preventive measures and environmental policies to safeguard public health.

Indexed as

AtherosclerosisCardiovascular diseaseEnvironmental pollutionPMToxic metals

Identifiers

PMID39328571
PMCPMC11425171

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.