Evidence map›Paper›PMID 39328753›Full record

ArticleJACS Au2024

Trapped in Cells: A Selective Accumulation Approach for Type-I Photodynamic Ablation of Cancer Stem-like Cells.

Ji Hyeon Kim, Jieun Lee, Kyung-Woo Lee, Hao Xiong, Mingle Li, Jong Seung Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ji Hyeon KimDepartment of Chemistry, Korea University, Seoul 02841, Korea.
Jieun LeeDepartment of Chemistry, Korea University, Seoul 02841, Korea.
Kyung-Woo LeeDepartment of Chemistry, Korea University, Seoul 02841, Korea.
Hao XiongDepartment of Chemistry, Korea University, Seoul 02841, Korea.
Mingle LiCollege of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.ORCID https://orcid.org/0000-0002-0384-9128
Jong Seung KimDepartment of Chemistry, Korea University, Seoul 02841, Korea.ORCID https://orcid.org/0000-0003-3477-1172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aldehyde dehydrogenase (ALDH) is an enzyme responsible for converting aldehyde functional groups into carboxylate metabolites. Elevated ALDH activity is a characteristic feature of cancer stem-like cells (CSCs). As a novel approach to target the CSC trait of overexpressing ALDH, we aimed to utilize ALDH activity for the selective accumulation of a photosensitizer in ALDH

Identifiers

PMID39328753
PMCPMC11423316

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.