Evidence map›Paper›PMID 39328774›Full record

ArticleJACS Au2024

Rational Design of Dual-Domain Binding Inhibitors for

Ismael Compañón, Collin J Ballard, Erandi Lira-Navarrete, Tanausú Santos, Serena Monaco, Juan C Muñoz-García, Ignacio Delso, Jesus Angulo, Thomas A Gerken, Katrine T Schjoldager and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ismael CompañónDepartment of Chemistry and Instituto de Investigación en Química de la Universidad de La Rioja, Universidad de La Rioja, Logroño 26006, Spain.
Collin J BallardDepartment of Biochemistry, Case Western Reserve University, 2109 Adelbert Rd, Cleveland, Ohio 44106, United States.ORCID https://orcid.org/0000-0003-2869-6970
Erandi Lira-NavarreteDepartment of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen 2200, Denmark.
Tanausú SantosDepartment of Chemistry and Instituto de Investigación en Química de la Universidad de La Rioja, Universidad de La Rioja, Logroño 26006, Spain.
Serena MonacoSchool of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, U.K.ORCID https://orcid.org/0000-0001-9396-7568
Juan C Muñoz-GarcíaSchool of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, U.K.ORCID https://orcid.org/0000-0003-2246-3236
Ignacio DelsoSchool of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, U.K.
Jesus AnguloSchool of Pharmacy, University of East Anglia, Norwich Research Park, NR4 7TJ Norwich, U.K.ORCID https://orcid.org/0000-0001-7250-5639
Thomas A GerkenDepartment of Biochemistry, Case Western Reserve University, 2109 Adelbert Rd, Cleveland, Ohio 44106, United States.
Katrine T SchjoldagerDepartment of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen 2200, Denmark.
Henrik ClausenDepartment of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen 2200, Denmark.
Tomás TejeroDepartment of Organic Chemistry, Faculty of Sciences, University of Zaragoza, Zaragoza 50009, Spain.ORCID https://orcid.org/0000-0003-3433-6701
Pedro MerinoDepartment of Organic Chemistry, Faculty of Sciences, University of Zaragoza, Zaragoza 50009, Spain.ORCID https://orcid.org/0000-0002-2202-3460
Francisco CorzanaDepartment of Chemistry and Instituto de Investigación en Química de la Universidad de La Rioja, Universidad de La Rioja, Logroño 26006, Spain.ORCID https://orcid.org/0000-0001-5597-8127
Ramon Hurtado-GuerreroDepartment of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen Center for Glycomics, University of Copenhagen, Copenhagen 2200, Denmark.ORCID https://orcid.org/0000-0002-3122-9401
Mattia GhirardelloDepartment of Chemistry and Instituto de Investigación en Química de la Universidad de La Rioja, Universidad de La Rioja, Logroño 26006, Spain.ORCID https://orcid.org/0000-0002-2855-4801

Funding

Initiation and Regulation of Mucin-Type O-GlycosylationR01GM113534 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI GERKEN, THOMAS A · 2018 to 2023
$1.6M
NIGMS NIH HHS R01 GM113534
6 · The paper itself

Abstract

The GalNAc-transferase (GalNAc-T) family, consisting of 20 isoenzymes, regulates the

Identifiers

PMID39328774
PMCPMC11423303

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.