ArticleHealth science reports2024
Evaluation of Pro-BNP biomarker in heart failure patients and its relationship with complete blood count parameters: A case-control study.
Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
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- Statistical approaches to make cardiac biomarkers compatible for efficient management of cardiovascular diseases in a regional medical care system.Journal of rural medicine : JRM · 2026Article
- Analysis of risk factors for heart failure in patients with type 2 diabetes mellitus and acute ST-segment elevation myocardial infarction after percutaneous coronary intervention.Frontiers in medicine · 2026Article
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Heart failure (HF) is a growing global health concern. N-terminal prohormone of brain natriuretic peptide (NT-pro-BNP) is an established biomarker for ventricular dysfunction in heart failure (HF). This case-control study examined the relationship between brain natriuretic peptide (Pro-BNP) levels and complete blood count (CBC) parameters in HF patients and healthy controls, exploring the utility of CBC as a supplementary diagnostic tool for HF. Methods: The study included 89 participants, divided into 42 HF patients with diagnosed HF (patient group) and 47 healthy individuals (control group). Pro-BNP levels were measured alongside a comprehensive CBC panel, including parameters such as white blood cell count, hemoglobin levels, and platelet count. Demographic, clinical characteristics, and CBC parameters were compared between the two groups, with statistical analyses performed to identify any significant associations. Results: The analysis demonstrated that HF patients had significantly higher Pro-BNP levels than the control subjects, indicating a strong association between Pro-BNP levels and HF (1052.65 [196.56] vs. 2500.34 [1105.90], Conclusion: Pro-BNP exhibits clinical relevance in diagnosing cardiovascular dysfunction, with elevated levels and distinct hematological profiles in HF patients. Pro-BNP's diagnostic and predictive capabilities for hematocrit and platelet count support its use in risk assessment and treatment decisions for HF.
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