Evidence map›Paper›PMID 39329062›Full record

ArticleFrontiers in cell and developmental biology2024

Standardization and quality assessment for human intestinal organoids.

Hana Lee, Seunghye Yang, Kyung Jin Lee, Si-Na Kim, Ji-Seon Jeong, Ki Young Kim, Cho-Rok Jung, Sooyeon Jeon, Dayeon Kwon, Sungin Lee and 5 more

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guiding Principles: Reporting Elements for Gastrointestinal Organoid Research.Cellular and molecular gastroenterology and hepatology · 2026
    Guideline
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Beyond monolayers: a comparative analysis of 2D cell cultures and 3DFrontiers in bioengineering and biotechnology · 2026
    Review
  13. Review
  14. Review
  15. A Shared Framework for Gastrointestinal Organoid Research: It's Time.Cellular and molecular gastroenterology and hepatology · 2026
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hana Lee *Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.
Seunghye Yang *Organoid Standards Initiative (OSI), Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Kyung Jin Lee *Organoid Standards Initiative (OSI), Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Si-Na KimORGANOIDSCIENCES, Seongnam-si, Republic of Korea.
Ji-Seon JeongOrganoid Standards Initiative (OSI), Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Ki Young KimOrganoid Standards Initiative (OSI), Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Cho-Rok JungKorea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.
Sooyeon JeonDigital Health Laboratory, Department of Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Dayeon KwonDigital Health Laboratory, Department of Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Sungin LeeDigital Health Laboratory, Department of Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Hanbyeol LeeDigital Health Laboratory, Department of Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Chihye ParkDigital Health Laboratory, Department of Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Sun-Ju AhnOrganoid Standards Initiative (OSI), Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Jongman YooOrganoid Standards Initiative (OSI), Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea.
Mi-Young SonKorea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To enhance the practical application of intestinal organoids, it is imperative to establish standardized guidelines. This proposed standardization outlines a comprehensive framework to ensure consistency and reliability in the development, characterization, and application of intestinal organoids. The recommended guidelines encompass crucial parameters, including culture conditions, critical quality attributes, quality control measures, and functional assessments, aimed at fostering a standardized approach across diverse research initiatives. The implementation of these guidelines is anticipated to significantly contribute to the reproducibility and comparability of results in the burgeoning field of intestinal organoid research.

Indexed as

guidelinehuman adult stem cell (hASC)human intestinal organoid (hIO)human pluripotent stem cell (hPSC)standardization

Identifiers

PMID39329062
PMCPMC11424408

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.