Evidence map›Paper›PMID 39329983›Full record

ArticleCurrent issues in molecular biology2024

The Role of Biomarkers in the Early Diagnosis of Gastric Cancer: A Study on CCR5, CCL5, PDGF, and EphA7.

Süleyman Bademler, Berkay Kılıç, Muhammed Üçüncü, Alisan Zirtiloglu, Burak İlhan

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In one paragraph

Article in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Süleyman BademlerDepartment of Surgery, Oncology Institute, Istanbul University, 34093 Istanbul, Turkey.
Berkay KılıçDepartment of Surgery, Oncology Institute, Istanbul University, 34093 Istanbul, Turkey.
Muhammed ÜçüncüDepartment of Health Science Institute, Istanbul Gelisim University, 34310 Istanbul, Turkey.ORCID 0000-0003-4638-1059
Alisan ZirtilogluDepartment of Medical Oncology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, 34147 Istanbul, Turkey.ORCID 0000-0002-3319-3983
Burak İlhanDepartment of Surgery, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.ORCID 0000-0002-7538-7399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the use of screening programs, gastric cancer (GC) diagnosis may only be possible at an advanced stage. In this study, we examined the serum levels of C-C chemokine receptor type 5 (CCR5), C-C motif chemokine ligand 5 (CCL5), platelet-derived growth factor (PDGF), and EphrinA7 (EphA7) in patients with gastric carcinoma and healthy controls to investigate the significance and usability of these potential biomarkers in the early diagnosis of GC. The study enrolled 69 GC patients and 40 healthy individuals. CCR5, CCL5, PDGF-BB, and EphA7 levels, which have been identified in the carcinogenesis of many cancers, were measured in the blood samples using the ELISA method. CCR5, CCL5, PDGF-BB, and EphA7 were all correlated with GC diagnosis (CCR5,

Indexed as

CCL5CCR5chemokinecytokineEphA7gastric cancerPDGF

Identifiers

PMID39329983
PMCPMC11430782

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.