Evidence map›Paper›PMID 39333385›Full record

ReviewMolecular psychiatry2025

Towards a neurodevelopmental model of bipolar disorder: a critical review of trait- and state-related functional neuroimaging in adolescents and young adults.

Lejla Colic, Anjali Sankar, Danielle A Goldman, Jihoon A Kim, Hilary P Blumberg

Abstract readReview
In one paragraph

Review in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Brain White Matter Microstructure in Middle and Older Aged Adults With Bipolar Disorder: A 2-Site Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
    Article
  5. Article
  6. Editorial: Neurodevelopment: parental influences,Frontiers in neuroscience · 2026
    Article
  7. Hippocampal Subregion Function and Its Clinical Correlations in Childhood Autism Spectrum Disorders.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lejla Colic *Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.ORCID 0000-0002-8809-4034
Anjali Sankar *Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-7517-9776
Danielle A GoldmanDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Jihoon A KimDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Hilary P BlumbergDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. hilary.blumberg@yale.edu.ORCID 0000-0002-6363-4698

Funding

NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)UG3MH111929 · NIMH · YALE UNIVERSITY · PI BLUMBERG, HILARY PATRICIA · 2018 to 2019
$943k
Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)R61MH111929 · NIMH · YALE UNIVERSITY · PI BLUMBERG, HILARY PATRICIA · 2017 to 2017
$750k
NCATS NIH HHS TL1 TR001864NIMH NIH HHS UG3 MH111929
6 · The paper itself

Abstract

Neurodevelopmental mechanisms are increasingly implicated in bipolar disorder (BD), highlighting the importance of their study in young persons. Neuroimaging studies have demonstrated a central role for frontotemporal corticolimbic brain systems that subserve processing and regulation of emotions, and processing of reward in adults with BD. As adolescence and young adulthood (AYA) is a time when fully syndromal BD often emerges, and when these brain systems undergo dynamic maturational changes, the AYA epoch is implicated as a critical period in the neurodevelopment of BD. Functional magnetic resonance imaging (fMRI) studies can be especially informative in identifying the functional neuroanatomy in adolescents and young adults with BD (BD

Indexed as

Bipolar DisorderAdolescentBrainBrain MappingFunctional NeuroimagingHumansMagnetic Resonance ImagingNeuroimagingYoung Adult

Identifiers

PMID39333385
PMCPMC11835756

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.