ArticleCommunications biology2024
Dim light at night unmasks sex-specific differences in circadian and autonomic regulation of cardiovascular physiology.
Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Circadian Systems and Neural Control of Blood Pressure.Current hypertension reports · 2026Review
- Dim light at night worsens cardiac autonomic dysregulation in female diabetic mice.Heart rhythm · 2026Article
- Dim light at night induces cardiac injury in zebrafish embryos via disrupted chloride homeostasis.iScience · 2026Article
- Article
- Chronic Night Shift Is More Detrimental Than Chronic Light at Night on Circadian Rhythmicity and Metabolic Health in a Female Diurnal Rodent.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability.Heart rhythm · 2026Article
- Dim light at night impacts circadian rhythms and Alzheimer's disease-like neuroinflammation and neuropathology in humanized APP SAA knock-in mice.bioRxiv : the preprint server for biology · 2025Article
- Circadian Rhythm Disruptions and Cardiovascular Disease Risk: The Special Role of Melatonin.Current issues in molecular biology · 2025Review
- Autonomic nervous system: an integrative regulator in circadian rhythm of blood pressure.Frontiers in neurologyReview
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Shift work and artificial light at night disrupt the entrainment of endogenous circadian rhythms in physiology and behavior to the day-night cycle. We hypothesized that exposure to dim light at night (dLAN) disrupts feeding rhythms, leading to sex-specific changes in autonomic signaling and day-night heart rate and blood pressure rhythms. Compared to mice housed in 12-hour light/12-hour dark cycles, mice exposed to dLAN showed reduced amplitudes in day-night feeding, heart rate, and blood pressure rhythms. In female mice, dLAN reduced the amplitude of day-night cardiovascular rhythms by decreasing the relative sympathetic regulation at night, while in male mice, it did so by increasing the relative sympathetic regulation during the daytime. Time-restricted feeding to the dim light cycle reversed these autonomic changes in both sexes. We conclude that dLAN induces sex-specific changes in autonomic regulation of heart rate and blood pressure, and time-restricted feeding may represent a chronotherapeutic strategy to mitigate the cardiovascular impact of light at night.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.