Evidence map›Paper›PMID 39334144›Full record

ArticleVirology journal2024

Characterization of multiple human papillomavirus types in the human vagina following ovarian hormonal stimulation.

Endrya do Socorro Foro Ramos, Roseane da Silva Couto, Tania Regina Tozetto-Mendoza, Pietro Bortoletto, Erick Matheus Garcia Barbosa, Noely Evangelista Ferreira, Iara M Linhares, Steven D Spandorfer, Antonio Charlys da Costa, Elcio Leal and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Endrya do Socorro Foro Ramos *Viral Diversity Laboratory, Institute of Biological Sciences, Federal University of Pará, Belem, Pará, Brazil.
Roseane da Silva Couto *Viral Diversity Laboratory, Institute of Biological Sciences, Federal University of Pará, Belem, Pará, Brazil.
Tania Regina Tozetto-Mendoza *Medical Research Laboratory in Virology (LIM 52), Faculty of Medicine, University of São Paulo-Institute of Tropical Medicine de São Paulo, São Paulo, Brazil.
Pietro Bortoletto *Boston IVF, Waltham, MA, USA.
Erick Matheus Garcia BarbosaMedical Research Laboratory in Virology (LIM 52), Faculty of Medicine, University of São Paulo-Institute of Tropical Medicine de São Paulo, São Paulo, Brazil.
Noely Evangelista FerreiraMedical Research Laboratory in Virology (LIM 52), Faculty of Medicine, University of São Paulo-Institute of Tropical Medicine de São Paulo, São Paulo, Brazil.
Iara M LinharesDepartment of Gynecology and Obstetrics, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Steven D SpandorferCenter for Reproductive Medicine and Infertility, Weill Cornell Medicine, New York, USA.
Antonio Charlys da Costa *Medical Research Laboratory in Virology (LIM 52), Faculty of Medicine, University of São Paulo-Institute of Tropical Medicine de São Paulo, São Paulo, Brazil. charlysbr@yahoo.com.br.
Elcio Leal *Viral Diversity Laboratory, Institute of Biological Sciences, Federal University of Pará, Belem, Pará, Brazil. elcioleal@gmail.com.
Maria Cassia Mendes-Correa *Medical Research Laboratory in Virology (LIM 52), Faculty of Medicine, University of São Paulo-Institute of Tropical Medicine de São Paulo, São Paulo, Brazil. maria.cassia@hc.fm.usp.br.
Steven S Witkin *Medical Research Laboratory in Virology (LIM 52), Faculty of Medicine, University of São Paulo-Institute of Tropical Medicine de São Paulo, São Paulo, Brazil. switkin@med.cornell.edu.

Funding

scholarship from HCFMUSP with funds donated by NUBANK under the #HCCOMVIDA scheme HCFMUSPscholarship provided by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil CAPES
6 · The paper itself

Abstract

The objective of study was to characterize HPV in vaginal samples from women being seen at the Center for Reproductive Medicine and Infertility at Weill Cornell Medicine before and following ovarian stimulation. A total of 29 women made samples available for analysis by viral metagenomics. Eighteen women were HPV-positive, six (33.3%) at their initial visit and 15 (83.3%) following hormone stimulation (p = 0.0059). Pairwise comparison of nucleotide sequences and phylogenetic analysis showed the classification sequences into two genera: Alphapapillomavirus and Gammapapillomavirus. Sequences were from 8 HPV types: HPV 51 (n = 2), HPV 68 (n = 1), HPV 83 (n = 9), HPV 84 (n = 2), HPV 121 (n = 6), HPV 175 (n = 1) and HPV 190 (n = 1). Additionally, C16b and C30 likely represent new types. In summary, multiple HPV types are present in the vagina of reproductive age women and are induced by hormone used to stimulate ovulation.

Indexed as

Ovulation InductionPapillomaviridaePapillomavirus InfectionsPhylogenyVaginaAdultDNA, ViralFemaleGenotypeHuman Papillomavirus VirusesHumansMetagenomicsSequence Analysis, DNAYoung AdultDNA, ViralAlphapapillomavirusGammapapillomavirusOvarian hormonal stimulationViral metagenomics

Identifiers

PMID39334144
PMCPMC11429140

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.