Evidence mapPaperPMID 39334174Full record

ArticleLipids in health and disease2024

Association between the age-adjusted visceral adiposity index (AVAI) and female infertility status: a cross-sectional analysis of the NHANES 2013-2018.

Mingqin Kuang, Ying Yu, Shanyang He

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Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

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12citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Mingqin KuangGuangdong Cardiovascular Institute, Guangzhou, Guangdong, 510080, People's Republic of China.
Ying YuGynecology and Oncology Department of Ganzhou Cancer Hospital, Ganzhou, Jiangxi, 341000, People's Republic of China.
Shanyang HeDepartment of Gynecology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510080, People's Republic of China. heshanyang@gdph.org.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity stands as an essential factor contributing to infertility in women. Early identification of obese individuals leads to favorable results for female infertility. The objective of this research is to assess the association between the age-adjusted visceral adiposity index (AVAI) and female infertility.

methodsThis study was conducted using NHANES data from 2013 to 2018, in which 1,231 women aged 20-45 were selected. Infertility was defined by survey questions. AVAI was calculated using anthropometric and serum data. Covariates included demographics and lifestyle factors. Statistical analysis with R, adjusting for covariates, and assessing nonlinearity and cutoff effects.

resultsThe study of 1,231 women from the NHANES database revealed that 11.94% were diagnosed with infertility. Individuals with higher AVAI scores showed increased age, WC, BMI, and reduced HDL levels, with a positive correlation between AVAI and female infertility (OR = 1.42, 95%CI: 1.26-1.60). AVAI quartiles showed a pronounced relationship with female infertility risk, with the highest quartile showing the greatest risk(OR = 9.35,95% CI: 2.96-29.55). Nonlinear and threshold effects in the relationship between AVAI and female infertility were identified, with an inflection point at -9.70. Subgroup analyses indicated significant interactions between AVAI and educational status and BMI, particularly in women with a BMI below 25 kg/m

conclusionThe study identifies a strong association between elevated AVAI scores and female infertility risk, especially in women with a BMI under 25 kg/m

Indexed as

AdiposityBody Mass IndexInfertility, FemaleIntra-Abdominal FatNutrition SurveysAdultAge FactorsCross-Sectional StudiesFemaleHumansMiddle AgedObesity, AbdominalRisk FactorsWaist CircumferenceYoung AdultAge-adjusted visceral adiposity indexBMIFemale infertilityNHANESObesity

Identifiers

PMID39334174
PMCPMC11438287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.