Evidence map›Paper›PMID 39334363›Full record

ReviewJournal of translational medicine2024

LINC01089 in cancer: multifunctional roles and therapeutic implications.

Qiang Yi, Gangfeng Zhu, Xinting Ouyang, Weijian Zhu, Kui Zhong, Zheng Chen, Jinghua Zhong

Abstract readReview
In one paragraph

Review in Journal of translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. ReducedInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiang Yi *The First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Gangfeng Zhu *The First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Xinting Ouyang *The First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Weijian ZhuThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Kui ZhongThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Zheng ChenThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
Jinghua ZhongDepartment of Oncology, The First Affiliated Hospital of Gannan Medical University, 128 Jinling Road, Ganzhou, 341000, Jiangxi, China. m18770738786@163.com.

Funding

National Natural Science Foundation of China 82260604Natural Science Foundation of Jiangxi Province 20192BAB205053
6 · The paper itself

Abstract

LINC01089 is a prime example of a long non-coding RNA that plays a pivotal role in the progression of human cancers. The gene encoding this lncRNA is located on 12q24.31. LINC01089 has been demonstrated to exert tumor-suppressive effects in various cancers, including colorectal cancer, gastric cancer, lung cancer, ovarian cancer, cervical cancer, papillary thyroid carcinoma, breast cancer, and osteosarcoma. However, its role in hepatocellular carcinoma shows significant discrepancies across different studies. In this review, we systematically explore the functions of LINC01089 in human cancers through bioinformatics analysis, clinical studies, animal models, and fundamental experimental research. Furthermore, we delve into the biological mechanisms and functions of LINC01089, and discuss its potential as a future biomarker and therapeutic target in detail.

Indexed as

NeoplasmsRNA, Long NoncodingAnimalsComputational BiologyGene Expression Regulation, NeoplasticHumansRNA, Long NoncodingBiologicalClinical therapiesLINC01089LncRNAMalignant cancers

Identifiers

PMID39334363
PMCPMC11429488

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.