Evidence mapPaperPMID 39334411Full record

Trial reportItalian journal of pediatrics2024

Effect of a prolonged slow expiration technique on 24-h food intake in children hospitalized for moderate bronchiolitis: a randomized controlled trial.

Yann Combret, Margaux Machefert, Mélody Couet, Tristan Bonnevie, Francis-Edouard Gravier, Timothée Gillot, Pascal Le Roux, Roger Hilfiker, Clément Medrinal, Guillaume Prieur

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Italian journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03738501 (Slow Expiratory Technique Efficacy on 24 Hours Food Ingestion in Children Under Than 12 Months, Hospitalized for Bronchiolitis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03738501 nacompletednot on this map

Slow Expiratory Technique Efficacy on 24 Hours Food Ingestion in Children Under Than 12 Months, Hospitalized for Bronchiolitis : a Randomized Controlled Study

TypeinterventionalSponsorGroupe Hospitalier du HavreRan2019 to 2022Enrolled42ConditionsAcute Viral BronchiolitisArmsChest physiotherapy with SET, Standard Treatment
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yann CombretPhysiotherapy Department, Le Havre Hospital, Le Havre, F-76600, France. yann.combret@gmail.com.ORCID http://orcid.org/0000-0003-1962-3331
Margaux MachefertPhysiotherapy Department, Le Havre Hospital, Le Havre, F-76600, France.
Mélody CouetSchool of Physiotherapy, Rouen University Hospital, Rouen, F-76000, France.
Tristan BonnevieUniv Rouen Normandie, Normandie Univ, GRHVN UR 3830, Rouen, F-76000, France.
Francis-Edouard GravierUniv Rouen Normandie, Normandie Univ, GRHVN UR 3830, Rouen, F-76000, France.
Timothée GillotSchool of Physiotherapy, Rouen University Hospital, Rouen, F-76000, France.
Pascal Le RouxPaediatric Department, Le Havre Hospital, Le Havre, F-76600, France.
Roger HilfikerResearch and Independent Studies in Private Physiotherapy (RISE), 3902, Brig, Switzerland.
Clément MedrinalPhysiotherapy Department, Le Havre Hospital, Le Havre, F-76600, France.
Guillaume PrieurPhysiotherapy Department, Le Havre Hospital, Le Havre, F-76600, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChest physiotherapy for airway clearance is not recommended in children hospitalized with bronchiolitis. The updated Cochrane meta-analysis suggests that slow expiratory techniques could slightly improve clinical severity, but the evidence certainty is low and the clinical significance of this change is unknown. We investigated whether the prolonged slow expiration technique (PSET) would impact the 24-h food intake of these children.

methodsWe conducted a two-arm double-blind randomized controlled trial. Hospitalized children aged from 1 to 12 months, bottle-fed or diversified and referred for airway clearance were included. Both groups received upper airway clearance at inclusion and standard treatments. The experimental group received PSET including rhinopharyngeal unclogging and targeted unprovoked cough. The primary outcome was the 24-h food intake. Clinical severity, vomit episodes and sleep quality were also recorded. An ordinary least squares linear regression for quantitative variables was modelled for between-group comparisons.

resultsFrom January 9, 2019, to December 1, 2022, 42 children were randomized with a 1:1 ratio (mean age: 5.0 (± 2.9) months). The 24-h food intake did not differ between groups (estimate: 1.8% (95%CI -7.0 to 10.6); p = 0.68). PSET had no effect on SpO2, clinical severity, RR and HR at the follow-up assessments (5 min, 30 min and 24 h after intervention), nor on the number of vomit episodes, total sleep time and SpO2 during sleep.

conclusionsPSET did not affect food intake or the 24-h course of bronchiolitis more than standard treatment in children hospitalized for moderate bronchiolitis.

trial registrationNCT03738501  registered on 13/11/2018, Slow Expiratory Technique to Improve Alimentation in Children With Bronchiolitis (BRONCHIOL-EAT); https://classic. CLINICALTRIALS: gov/ct2/show/NCT03738501.

Indexed as

BronchiolitisEatingExhalationRespiratory TherapyDouble-Blind MethodFemaleHospitalizationHumansInfantMaleSeverity of Illness IndexAcute viral bronchiolitisAirway clearance techniquesChest physiotherapyFeeding issues

Identifiers

PMID39334411
PMCPMC11438082

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.