Evidence map›Paper›PMID 39334865›Full record

ArticleBiomolecules2024

Biochemical Characterisation of the Short Isoform of Histone N-Terminal Acetyltransferase NAA40.

Ariel Klavaris, Maria Kouma, Cem Ozdemir, Vicky Nicolaidou, Kyle M Miller, Costas Koufaris, Antonis Kirmizis

Abstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ariel KlavarisEpigenetics and Gene Regulation Laboratory, Department of Biological Sciences, University of Cyprus, Nicosia 2109, Cyprus.
Maria KoumaEpigenetics and Gene Regulation Laboratory, Department of Biological Sciences, University of Cyprus, Nicosia 2109, Cyprus.
Cem OzdemirDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.ORCID 0009-0009-9501-503X
Vicky NicolaidouDepartment of Life Sciences, University of Nicosia, Nicosia 2417, Cyprus.ORCID 0000-0003-1017-2677
Kyle M MillerDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.ORCID 0000-0002-4544-0013
Costas KoufarisEpigenetics and Gene Regulation Laboratory, Department of Biological Sciences, University of Cyprus, Nicosia 2109, Cyprus.ORCID 0000-0002-1222-5130
Antonis KirmizisEpigenetics and Gene Regulation Laboratory, Department of Biological Sciences, University of Cyprus, Nicosia 2109, Cyprus.ORCID 0000-0002-3748-8711

Funding

Shaping DNA Damage Response Networks Via Histone H2A VariantsR01CA198279 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI Kyle M Miller · 2016 to 2026
$3.3M
Mechanisms of Endogenous DNA Damage PromotionR01CA250905 · NCI · BAYLOR COLLEGE OF MEDICINE · PI MILLER, KYLE M, ROSENBERG, SUSAN M · 2020 to 2024
$3.3M
Cancer Prevention and Research Institute of Texas RP220330Cyprus Cancer Research Institute (C.C.R.I): Bridges in research excellence grant CCRI_2020_FUN_001-103NCI NIH HHS R01 CA198279NCI NIH HHS R01 CA250905NCI NIH HHS RO1 CA198279 and CA250905Research and Innovation Foundation EXCELLENCE/ 0421/0152
6 · The paper itself

Abstract

N-alpha-acetyltransferase 40 (NAA40) is an evolutionarily conserved N-terminal acetyltransferase (NAT) linked to oncogenesis and chemoresistance. A recent study reported the generation of a second, shorter NAA40 isoform (NAA40

Indexed as

HistonesAnimalsHEK293 CellsHumansIsoenzymesN-Terminal Acetyltransferase EProtein IsoformsHistonesIsoenzymesN-Terminal Acetyltransferase EProtein Isoformsenzymatic assayisoformNAA40testis

Identifiers

PMID39334865
PMCPMC11430322

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.